Evidence map›Paper›PMID 30830561›Full record

SynthesisSports medicine (Auckland, N.Z.)2019

Relative Efficacy of Different Exercises for Pain, Function, Performance and Quality of Life in Knee and Hip Osteoarthritis: Systematic Review and Network Meta-Analysis.

Siew-Li Goh, Monica S M Persson, Joanne Stocks, Yunfei Hou, Nicky J Welton, Jianhao Lin, Michelle C Hall, Michael Doherty, Weiya Zhang

3 registry-linked trialsAbstract readSystematic ReviewNetwork Meta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Sports medicine (Auckland, N.Z.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 98 papers, 22 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
98citing papers in PubMed, 22 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04496622 nacompletednot on this map

Comparison of Different Frequencies of Whole Body Vibration Training on Physical Function and Muscle Strength in Patients With Knee Osteoarthritis

TypeinterventionalSponsorRiphah International UniversityRan2019 to 2020Enrolled29ConditionsKnee OsteoarthritisArmsWBV technique, Whole body vibration technique
NCT04546659 nacompletednot on this mapstarted 2020, after this paper: background citation

Effects of Retro-walking on Pain, Functional Disability and Performance in Knee Osteoarthritis

TypeinterventionalSponsorRiphah International UniversityRan2020 to 2021Enrolled34ConditionsKnee OsteoarthritisArmsRetrowalking, Conventional Therapy
NCT05375565 nacompletednot on this mapstarted 2021, after this paper: background citation

Comparative Effects of Weight Bearing and Non-weight Bearing Exercises on Pain, Range of Motion and Disability in Patients With Total Hip Replacement

TypeinterventionalSponsorRiphah International UniversityRan2021 to 2022Enrolled22ConditionsTotal Hip ReplacementArmsweight bearing exercises, non weight bearing exercises
3 · Its place in the literature

Who cites it

98 citing papers in PubMed, 22 syntheses or guidelines pooled it.

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38 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Siew-Li GohArthritis Research UK Pain Centre, Academic Rheumatology, University of Nottingham, Clinical Sciences Building, City Hospital, Nottingham, NG5 1PB, UK.ORCID http://orcid.org/0000-0001-5898-1196
Monica S M PerssonArthritis Research UK Pain Centre, Academic Rheumatology, University of Nottingham, Clinical Sciences Building, City Hospital, Nottingham, NG5 1PB, UK.
Joanne StocksArthritis Research UK Pain Centre, Academic Rheumatology, University of Nottingham, Clinical Sciences Building, City Hospital, Nottingham, NG5 1PB, UK.
Yunfei HouDepartment of Orthopaedic Surgery, Peking University People's Hospital, Beijing, China.
Nicky J WeltonPopulation Health Sciences, University of Bristol, Bristol, UK.
Jianhao LinDepartment of Orthopaedic Surgery, Peking University People's Hospital, Beijing, China.
Michelle C HallDivision of Physiotherapy Rehabilitation Sciences Education, University of Nottingham, Nottingham, UK.
Michael DohertyArthritis Research UK Pain Centre, Academic Rheumatology, University of Nottingham, Clinical Sciences Building, City Hospital, Nottingham, NG5 1PB, UK.
Weiya ZhangArthritis Research UK Pain Centre, Academic Rheumatology, University of Nottingham, Clinical Sciences Building, City Hospital, Nottingham, NG5 1PB, UK. Weiya.Zhang@nottingham.ac.uk.

Funding

Arthritis Research UK (GB) Centre for Sports, Exercise and Osteoarthritis 21595Arthritis Research UK (GB) Pain Centre 20777Medical Research Council MR/K025643/1Medical Research Council MR/M005615/1
6 · The paper itself

Abstract

backgroundGuidelines recommend exercise as a core treatment for osteoarthritis (OA). However, it is unclear which type of exercise is most effective, leading to inconsistency between different recommendations.

objectivesThe aim of this systematic review and network meta-analysis was to investigate the relative efficacy of different exercises (aerobic, mind-body, strengthening, flexibility/skill, or mixed) for improving pain, function, performance and quality of life (QoL) for knee and hip OA at, or nearest to, 8 weeks.

methodsWe searched nine electronic databases up until December 2017 for randomised controlled trials that compared exercise with usual care or with another exercise type. Bayesian network meta-analysis was used to estimate the relative effect size (ES) and corresponding 95% credibility interval (CrI) (PROSPERO registration: CRD42016033865).

findingsWe identified and analysed 103 trials (9134 participants). Aerobic exercise was most beneficial for pain (ES 1.11; 95% CrI 0.69, 1.54) and performance (1.05; 0.63, 1.48). Mind-body exercise, which had pain benefit equivalent to that of aerobic exercise (1.11; 0.63, 1.59), was the best for function (0.81; 0.27, 1.36). Strengthening and flexibility/skill exercises improved multiple outcomes at a moderate level. Mixed exercise was the least effective for all outcomes and had significantly less pain relief than aerobic and mind-body exercises. The trend was significant for pain (p = 0.01), but not for function (p = 0.07), performance (p = 0.06) or QoL (p = 0.65).

conclusionThe effect of exercise varies according to the type of exercise and target outcome. Aerobic or mind-body exercise may be the best for pain and function improvements. Strengthening and flexibility/skill exercises may be used for multiple outcomes. Mixed exercise is the least effective and the reason for this merits further investigation.

Indexed as

Bayes TheoremExercise TherapyHumansOsteoarthritis, HipOsteoarthritis, KneePain ManagementQuality of LifeRandomized Controlled Trials as Topic

Identifiers

PMID30830561
PMCPMC6459784

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.