Evidence map›Paper›PMID 30833336›Full record

ArticleInfection and immunity2019

The Mouse Inhalation Model of

Liliane Mukaremera, Tami R McDonald, Judith N Nielsen, Christopher J Molenaar, Andrew Akampurira, Charlotte Schutz, Kabanda Taseera, Conrad Muzoora, Graeme Meintjes, David B Meya and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in Infection and immunity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 1 pooled it
5.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 1 synthesis or guideline pooled it, 70 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Journal of medical microbiology · 2026
    Article
  8. Stromal Cell-Mast Cell Communication Orchestrates Anti-Viral Immunity in the Meninges.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  9. Article
  10. Article
  11. Article
  12. Insights from Mass Spectrometry-Based Proteomics onJournal of fungi (Basel, Switzerland) · 2025
    Review
  13. The hypervirulent Type-1/Type-17 phenotype ofInfection and immunity · 2025
    Article
  14. Article
  15. Article
  16. Article
  17. Discovery of CONature microbiology · 2024
    Article
  18. Article
  19. Inbred Mouse Models inJournal of fungi (Basel, Switzerland) · 2024
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 3 countries.

Liliane MukaremeraDepartment of Microbiology and Immunology, University of Minnesota, Minneapolis, Minnesota, USA.
Tami R McDonaldBiology Department, St. Catherine University, St. Paul, Minnesota, USA.
Judith N NielsenDepartment of Pathology and Laboratory Medicine, University of North Carolina-Chapel Hill, Chapel Hill, North Carolina, USA.
Christopher J MolenaarDepartment of Microbiology and Immunology, University of Minnesota, Minneapolis, Minnesota, USA.
Andrew AkampuriraInfectious Diseases Institutes and School of Medicine, College of Health Sciences, Makerere University, Kampala, Uganda.
Charlotte SchutzDepartment of Medicine, University of Cape Town and Groote Schuur Hospital, Cape Town, South Africa.
Kabanda TaseeraDepartment of Medicine, Mbarara University of Science and Technology, Mbarara, Uganda.
Conrad MuzooraDepartment of Medicine, Mbarara University of Science and Technology, Mbarara, Uganda.
Graeme MeintjesDepartment of Medicine, University of Cape Town and Groote Schuur Hospital, Cape Town, South Africa.
David B MeyaInfectious Diseases Institutes and School of Medicine, College of Health Sciences, Makerere University, Kampala, Uganda.
David R BoulwareDepartment of Medicine, University of Minnesota, Minneapolis, Minnesota, USA.
Kirsten NielsenDepartment of Microbiology and Immunology, University of Minnesota, Minneapolis, Minnesota, USA knielsen@umn.edu.
University of Minnesota · USInfectious Diseases Institute · UGMbarara University of Science and Technology · UGGroote Schuur Hospital · ZASt. Catherine University · USUniversity of Cape Town · ZAUniversity of North Carolina at Chapel Hill · US

Funding

Virology Research Program (Program 4)P30CA016086 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Deborah F. Tate · 1985 to 2026
$201.5M
University of Minnesota Clinical and Translational Science Institute (UMN CTSI)UL1TR000114 · NCATS · UNIVERSITY OF MINNESOTA · PI BLAZAR, BRUCE R · 2012 to 2015
$35.0M
Trial for the Optimal Timing of HIV Therapy after Cryptococcal MeningitisU01AI089244 · NIAID · UNIVERSITY OF MINNESOTA · PI BOULWARE, DAVID R · 2010 to 2014
$7.6M
Northern/Pacific Universities Global Health Research Training ConsortiumR25TW009345 · FIC · UNIVERSITY OF WASHINGTON · PI KOLARS, JOSEPH C., NERURKAR, VIVEK RAMCHANDRA · 2012 to 2016
$5.9M
Impact of Cryptococcus Titan Cells on Pathogenesis.R01AI134636 · NIAID · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI Kirsten Nielsen · 2018 to 2026
$4.6M
Control of cryptococcal infection through manipulation of the host immune response.R21AI122352 · NIAID · UNIVERSITY OF MINNESOTA · PI NIELSEN, KIRSTEN · 2016 to 2017
$419k
Genomic Research Capacity Building for Cryptococcosis Translational StudiesR21NS108715 · NINDS · UNIVERSITY OF MINNESOTA · PI BAZIRA, JOEL, NIELSEN, KIRSTEN · 2018 to 2019
$352k
FIC NIH HHS R25 TW009345Medical Research Council MR/M007413/1NCATS NIH HHS UL1 TR000114NCI NIH HHS P30 CA016086NIAID NIH HHS R01 AI134636NIAID NIH HHS R21 AI122352NIAID NIH HHS U01 AI089244NINDS NIH HHS R21 NS108715
6 · The paper itself

Abstract

Cryptococcal meningitis (CM) causes high rates of HIV-related mortality, yet the

Indexed as

AnimalsCryptococcus neoformansDisease Models, AnimalGenetic VariationHIV InfectionsHost-Pathogen InteractionsHumansMeningitis, CryptococcalMiceVirulencecryptococcosisCryptococcusCryptococcus neoformanshumanmeningitismodelmousepathogenesissequence typevirulence

Identifiers

PMID30833336
PMCPMC6479045
OpenAlexW2919085913

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.