Evidence map›Paper›PMID 30833408›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2019

Renal control of disease tolerance to malaria.

Susana Ramos, Ana Rita Carlos, Balamurugan Sundaram, Viktoria Jeney, Ana Ribeiro, Raffaella Gozzelino, Claudia Bank, Erida Gjini, Faouzi Braza, Rui Martins and 12 more

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 1 pooled it
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 1 synthesis or guideline pooled it, 81 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Heme oxygenase-1 and malaria pathogenesis.Frontiers in immunology · 2026
    Review
  6. Molecular Mechanisms of Sepsis-Associated Acute Kidney Injury.Journal of the American Society of Nephrology : JASN · 2025
    Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. CD8Frontiers in cellular and infection microbiology · 2025
    Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 4 institutions in 3 countries.

Susana RamosInstituto Gulbenkian de Ciência, 2780-156 Oeiras, Portugal.
Ana Rita CarlosInstituto Gulbenkian de Ciência, 2780-156 Oeiras, Portugal.
Balamurugan SundaramInstituto Gulbenkian de Ciência, 2780-156 Oeiras, Portugal.
Viktoria JeneyFaculty of Medicine, Department of Internal Medicine, University of Debrecen, H-4032, Debrecen, Hungary.ORCID 0000-0003-4942-7091
Ana RibeiroInstituto Gulbenkian de Ciência, 2780-156 Oeiras, Portugal.
Raffaella GozzelinoInstituto Gulbenkian de Ciência, 2780-156 Oeiras, Portugal.
Claudia BankInstituto Gulbenkian de Ciência, 2780-156 Oeiras, Portugal.
Erida GjiniInstituto Gulbenkian de Ciência, 2780-156 Oeiras, Portugal.
Faouzi BrazaInstituto Gulbenkian de Ciência, 2780-156 Oeiras, Portugal.
Rui MartinsInstituto Gulbenkian de Ciência, 2780-156 Oeiras, Portugal.
Temitope Wilson AdemolueInstituto Gulbenkian de Ciência, 2780-156 Oeiras, Portugal.
Birte BlankenhausInstituto Gulbenkian de Ciência, 2780-156 Oeiras, Portugal.
Zélia GouveiaInstituto Gulbenkian de Ciência, 2780-156 Oeiras, Portugal.
Pedro FaíscaInstituto Gulbenkian de Ciência, 2780-156 Oeiras, Portugal.
Damian TrujilloDepartment of Microbiology and Immunology, Stanford University, Stanford, CA 94305-5124.
Sílvia CardosoInstituto Gulbenkian de Ciência, 2780-156 Oeiras, Portugal.
Sofia RebeloInstituto Gulbenkian de Ciência, 2780-156 Oeiras, Portugal.
Laura Del BarrioInstituto Gulbenkian de Ciência, 2780-156 Oeiras, Portugal.
Abolfazl ZarjouDepartment of Medicine, Division of Nephrology, University of Alabama, Birmingham, AL 35294.
Subhashini BolisettyDepartment of Medicine, Division of Nephrology, University of Alabama, Birmingham, AL 35294.
Anupam AgarwalDepartment of Medicine, Division of Nephrology, University of Alabama, Birmingham, AL 35294.
Miguel P SoaresInstituto Gulbenkian de Ciência, 2780-156 Oeiras, Portugal; mpsoares@igc.gulbenkian.pt.ORCID 0000-0002-9314-4833
Instituto Gulbenkian de Ciência · PTUniversity of Alabama · USStanford University · USUniversity of Debrecen · HU

Funding

UAB-UCSD O'Brien Core Center for Acute Kidney Injury ResearchP30DK079337 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI MEHTA, RAVINDRA L. · 2008 to 2022
$18.3M
Human Heme Oxygenase-1 Gene Regulation in Renal InjuryR01DK059600 · NIDDK · UNIVERSITY OF FLORIDA · PI AGARWAL, ANUPAM, GEORGE, JAMES F · 2002 to 2019
$4.5M
Targeting Ferritin in Vascular Calcification Associated With CKDK08HL140294 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ZARJOU, ABOLFAZL · 2018 to 2022
$841k
Ferritin mediates epithelial cell-macrophage cross talk in acute kidney injuryK01DK103931 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BOLISETTY, SUBHASHINI · 2014 to 2018
$752k
NHLBI NIH HHS K08 HL140294NIDDK NIH HHS K01 DK103931NIDDK NIH HHS P30 DK079337NIDDK NIH HHS R01 DK059600
6 · The paper itself

Abstract

Malaria, the disease caused by

Indexed as

AnimalsApoferritinsCell LineDisease ProgressionEpithelial CellsFerritinsHemeHeme Oxygenase-1HumansImmune ToleranceKidneyMalariaMiceMice, Inbred C57BLNF-E2-Related Factor 2OxidoreductasesApoferritinsFerritinsFTH1 protein, humanHemeHeme Oxygenase-1HMOX1 protein, humanNF-E2-Related Factor 2Oxidoreductasesdisease tolerancehemeinfectionkidneymalaria

Identifiers

PMID30833408
PMCPMC6431151
OpenAlexW2919759006

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.