ArticleBMC nephrology2019
Prevalence and factors associated with renal dysfunction in children admitted to two hospitals in northwestern Tanzania.
Article in BMC nephrology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 15 citations in OpenAlex.
- Prevalence, associated factors, and immediate outcomes of acute kidney injury in critically ill children in Tanzania.Pediatric nephrology (Berlin, Germany) · 2026Article
- Prevalence, predictors and outcomes of renal dysfunction among children with malignancy on chemotherapy at tertiary hospitals in Tanzania.BMC pediatrics · 2026Article
- Burden and severity of deranged electrolytes and kidney function in children seen in a tertiary hospital in Kano, northern Nigeria.PloS one · 2023Article
- Factors Associated with Acute Kidney Injury among Children with Severe Malaria at Kiryandongo General Hospital, Uganda.International journal of pediatrics · 2023Article
- Pharmacokinetics of Antimicrobials in Children with Emphasis on Challenges Faced by Low and Middle Income Countries, a Clinical Review.Antibiotics (Basel, Switzerland) · 2022Review
- Incidence and epidemiology of acute kidney injury in a pediatric Malawian trauma cohort: a prospective observational study.BMC nephrology · 2020Observational
- Mortality during and following hospital admission among school-aged children: a cohort study.Wellcome open research · 2020Article
- Prevalence and factors that are associated with elevated blood pressure among primary school children in Mwanza Region, Tanzania.The Pan African medical journal · 2020Article
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIt is evident that renal dysfunction (RD) is associated with unique infectious and non-infectious causes in African children. However, little data exists about the prevalence and factors associated with RD in children admitted to African hospitals.
methodsIn this cross-sectional study, we enrolled all children admitted to pediatric wards of Bugando Medical Centre (BMC) and Sekou-Toure Regional Referral hospital (SRRH) during a 6 month time period. Socio-demographical, clinical and laboratory data were collected using a structured questionnaire. Estimated glomerular filtration rate (eGFR) was calculated using modified Schwartz equation and those with < 60 ml/min/1.73m
resultsA total of 513 children were enrolled, of which 297 (57.9%) were males. Median age of children with and without RD was 34 months (27-60) and 46.5 (29-72) respectively. Prevalence of RD was 16.2%. Factors associated with RD were herbal medication use (p = 0.007), history of sore throat or skin infection (p = 0.024), sickle cell disease (SCD) (p = 0.006), dehydration (p = 0.001), malaria (p = 0.01) and proteinuria (p = < 0.001).
conclusionsHigh prevalence of RD was observed among children admitted to referral hospitals in Mwanza. Screening for RD should be performed on admitted children, particularly those with history of herbal medication use, sore throat/skin infection, SCD, dehydration and malaria. Where creatinine measurement is not possible, screening for proteinuria is a reasonable alternative.
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