Evidence map›Paper›PMID 30838874›Full record

ArticleAmerican journal of physiology. Renal physiology2019

TRPV4 deletion protects against hypokalemia during systemic K

Viktor Tomilin, Mykola Mamenko, Oleg Zaika, Charles S Wingo, Oleh Pochynyuk

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of physiology. Renal physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Intercalated Cell ClC-K2 Channel Contributes to Systemic ClFASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
  3. Review
  4. TRPV4 expression in the renal tubule is necessary for maintaining whole body KAmerican journal of physiology. Renal physiology · 2023
    Article
  5. Article
  6. Potassium homeostasis: sensors, mediators, and targets.Pflugers Archiv : European journal of physiology · 2022
    Review
  7. ClC-K2 ClFASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Viktor TomilinDepartment of Integrative Biology and Pharmacology, University of Texas Health Science Center at Houston , Houston, Texas.
Mykola MamenkoDepartment of Physiology, Medical College of Georgia, Augusta University , Augusta, Georgia.ORCID 0000-0001-8683-0715
Oleg ZaikaDepartment of Integrative Biology and Pharmacology, University of Texas Health Science Center at Houston , Houston, Texas.
Charles S WingoDivision of Nephrology, Hypertension and Transplantation, Department of Medicine, University of Florida , Gainesville, Florida.
Oleh PochynyukDepartment of Integrative Biology and Pharmacology, University of Texas Health Science Center at Houston , Houston, Texas.
The University of Texas Health Science Center at Houston · USAugusta University · USUniversity of Florida · US

Funding

Regulation of K+ balance by distal nephron TRPV4 channelR01DK119170 · NIDDK · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI POCHYNYUK, OLEH · 2018 to 2022
$1.7M
NIDDK NIH HHS R01 DK119170
6 · The paper itself

Abstract

Tight regulation of K

Indexed as

Renal ReabsorptionAnimalsDisease Models, AnimalFemaleGene DeletionHydrogen-Ion ConcentrationHypokalemiaKidney Tubules, CollectingMaleMice, Inbred C57BLMice, KnockoutPotassium DeficiencyPotassium, DietarySodium-Potassium-Exchanging ATPaseTRPV Cation ChannelsPotassium, DietarySodium-Potassium-Exchanging ATPaseTrpv4 protein, mouseTRPV Cation Channelscollecting ductintercalated cellsintracellular pHK transportprincipal cells

Identifiers

PMID30838874
PMCPMC6580258
OpenAlexW2921440443

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.