ArticleAmerican journal of respiratory and critical care medicine2019
IL4Rα Signaling Abrogates Hypoxic Neutrophil Survival and Limits Acute Lung Injury Responses
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Article in American journal of respiratory and critical care medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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0cells of the map it votes in
38citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
38 citing papers in PubMed, 53 citations in OpenAlex.
- Mucus plugs-associated gene expression identifies pathophysiology shared with chronic bronchitis.American journal of respiratory and critical care medicine · 2026Article
- Liposomes as carriers for garlic oil delivery to increase anti-inflammatory and antioxidant activities in mice with ALI.Experimental biology and medicine (Maywood, N.J.) · 2026Article
- Excessive Kynurenine Metabolism Impairs Lysosomal acidification and Triggers mtDNA Release via the AHR/CISH/ATP6V1A Axis in Decidual Macrophages Associated with Unexplained Recurrent Pregnancy Loss.International journal of biological sciences · 2026Article
- Neutrophil-macrophage crosstalk network in acute lung injury: feedback circuits linking cytokine storm and cell death.Frontiers in cellular and infection microbiology · 2026Review
- Emerging roles of basophils in the resolution of acute respiratory distress syndrome.The European respiratory journal · 2025Article
- HIF-1α: a bridge connecting sepsis and acute respiratory distress syndrome.European journal of medical research · 2025Review
- Comparative Immunomodulatory Efficacy of Secukinumab and Honokiol in Experimental Asthma and Acute Lung Injury.Pharmaceuticals (Basel, Switzerland) · 2025Article
- Advances in acute respiratory distress syndrome: focusing on heterogeneity, pathophysiology, and therapeutic strategies.Signal transduction and targeted therapy · 2025Review
- How oxygenation shapes immune responses: emerging roles for physioxia and pathological hypoxia.Nature reviews. Immunology · 2025Review
- Farrerol inhibits ferroptosis and protects against LPS-induced acute lung injury by targeting the RUNX1/SLC7A11 axis.Frontiers in immunology · 2025Article
- Expression and Regulation of Hypoxia-Inducible Factor Signalling in Acute Lung Inflammation.Cells · 2024Review
- Not just sugar: metabolic control of neutrophil development and effector functions.Journal of leukocyte biology · 2024Review
- Crtc1 deficiency protects against sepsis-associated acute lung injury through activating akt signaling pathway.Journal of inflammation (London, England) · 2024Article
- Progress in cytokine research for ARDS: A comprehensive review.Open medicine (Warsaw, Poland) · 2024Review
- New findings on CD16Frontiers in immunology · 2024Observational
- The Application of Drugs and Nano-Therapies Targeting Immune Cells in Hypoxic Inflammation.International journal of nanomedicine · 2024Review
- IL-4/IL-4 Ab complex enhances the accumulation of both antigen-specific and bystander CD8 T cells in mouse lungs infected with influenza A virus.Laboratory animal research · 2023Article
- Differences in Mortality Among Patients With Asthma and COPD Hospitalized With COVID-19.The journal of allergy and clinical immunology. In practice · 2023Article
- Biomolecular and cellular effects in skin wound healing: the association between ascorbic acid and hypoxia-induced factor.Journal of biological engineering · 2023Review
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Authors and funding
22 authors at 3 institutions in 3 countries.
Alison J Harris1 Medical Research Council/University of Edinburgh Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom.
Ananda S Mirchandani1 Medical Research Council/University of Edinburgh Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom.
Ruairi W Lynch1 Medical Research Council/University of Edinburgh Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom.
Fiona Murphy1 Medical Research Council/University of Edinburgh Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom.
Liam Delaney1 Medical Research Council/University of Edinburgh Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom.
Donna Small2 School of Medicine, Dentistry and Biomedical Sciences, Centre for Experimental Medicine, Queen's University of Belfast, Belfast, United Kingdom.
Patricia Coelho1 Medical Research Council/University of Edinburgh Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom.
Emily R Watts1 Medical Research Council/University of Edinburgh Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom.
Pranvera Sadiku1 Medical Research Council/University of Edinburgh Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom.
David Griffith1 Medical Research Council/University of Edinburgh Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom.ORCID 0000-0001-9500-241X
Rebecca S Dickinson1 Medical Research Council/University of Edinburgh Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom.
Eilidh Clark1 Medical Research Council/University of Edinburgh Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom.
Joseph A Willson1 Medical Research Council/University of Edinburgh Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom.
Tyler Morrison1 Medical Research Council/University of Edinburgh Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom.
Massimilliano Mazzone3 Laboratory of Tumour Inflammation and Angiogenesis, Department of Oncology, Leuven, Belgium; and.
Peter Carmeliet4 Laboratory of Angiogenesis and Vascular Metabolism, Vesalius Research Centre, Leuven, Belgium.
Bart Ghesquiere4 Laboratory of Angiogenesis and Vascular Metabolism, Vesalius Research Centre, Leuven, Belgium.
Cecilia O'Kane2 School of Medicine, Dentistry and Biomedical Sciences, Centre for Experimental Medicine, Queen's University of Belfast, Belfast, United Kingdom.
Danny McAuley2 School of Medicine, Dentistry and Biomedical Sciences, Centre for Experimental Medicine, Queen's University of Belfast, Belfast, United Kingdom.
Steve J Jenkins1 Medical Research Council/University of Edinburgh Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom.
Moira K B Whyte1 Medical Research Council/University of Edinburgh Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom.
Sarah R Walmsley1 Medical Research Council/University of Edinburgh Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom.ORCID 0000-0001-9584-174X
Centre for Inflammation Research · GBAngiogenesis Foundation · USQueen's University Belfast · GB
Funding
Medical Research Council MR/N02995X/1Wellcome Trust 098516Wellcome Trust 110086Wellcome Trust 110086/Z/15/ZWellcome Trust 209220Wellcome Trust 209220/Z/17/Z
Abstract
PubMed holds no abstract for this paper.
Indexed as
Acute Lung InjuryAnimalsApoptosisCell HypoxiaCell SurvivalGene Expression RegulationHumansHypoxia-Inducible Factor 1, alpha SubunitInterleukin-4Interleukin-4 Receptor alpha SubunitMiceMice, KnockoutNeutrophilsReceptors, Cell SurfaceRespiratory Distress SyndromeSignal TransductionHypoxia-Inducible Factor 1, alpha SubunitIl4ra protein, mouseIL4R protein, humanInterleukin-4Interleukin-4 Receptor alpha SubunitReceptors, Cell SurfaceSTAT Transcription Factorsacute respiratory distress syndromehypoxiahypoxia-inducible factor-1αIL-4neutrophil
Identifiers
What Socratic holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.