Evidence map›Paper›PMID 30849983›Full record

ReviewMolecular cancer2019

The role of exosomal noncoding RNAs in cancer.

Yan Xie, Wei Dang, Siwei Zhang, Wenxing Yue, Li Yang, Xingyu Zhai, Qijia Yan, Jianhong Lu

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Molecular cancer, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 161 papers.

0numbers the graph read from it
0cells of the map it votes in
161citing papers in PubMed
13.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

161 citing papers in PubMed, 230 citations in OpenAlex.

  1. Article
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  9. The role of exosomes in bladder cancer immunotherapy.Journal of the National Cancer Center · 2025
    Review
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101 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Yan XieDepartment of Pathology, Xiangya Hospital, Central South University, Changsha, 410080, China.
Wei DangDepartment of Pathology, Xiangya Hospital, Central South University, Changsha, 410080, China.
Siwei ZhangDepartment of Pathology, Xiangya Hospital, Central South University, Changsha, 410080, China.
Wenxing YueDepartment of Pathology, Xiangya Hospital, Central South University, Changsha, 410080, China.
Li YangDepartment of Pathology, Xiangya Hospital, Central South University, Changsha, 410080, China.
Xingyu ZhaiDepartment of Pathology, Xiangya Hospital, Central South University, Changsha, 410080, China.
Qijia YanDepartment of Pathology, Xiangya Hospital, Central South University, Changsha, 410080, China.
Jianhong LuDepartment of Pathology, Xiangya Hospital, Central South University, Changsha, 410080, China. jianhlu@csu.edu.cn.
Xiangya Hospital Central South University · CNCentral South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Extracellular vesicles (EVs) membranes enclose nanosized vesicles with a size range of 30-150 nm and are plentiful in our body in both physiological and pathological conditions. Exosomes, a type of EV, are important mediators of intracellular communication among tumor cells, immune cells, and stromal cells. They can shuttle bioactive molecules, such as proteins, lipids, RNA, and DNA; however, the precise function of EVs remains largely unknown. In recent years, tumor-associated cargo in exosomes has been a hot topic in research, especially with respect to noncoding RNAs (ncRNAs). Herein, we review the role of exosomal ncRNAs, including miRNAs and long noncoding RNAs, in tumor biological processes. Clinically, exosomal ncRNAs may eventually become novel biomarkers and therapeutic targets in cancer progression.

Indexed as

Cell CommunicationGene Expression Regulation, NeoplasticAnimalsExosomesHumansNeoplasmsRNA, UntranslatedRNA, UntranslatedCancerExosomesFunctionNoncoding RNAs

Identifiers

PMID30849983
PMCPMC6408816
OpenAlexW2936583550

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.