SynthesisJournal of biophotonics2019
Intraoperative multispectral and hyperspectral label-free imaging: A systematic review of in vivo clinical studies.
Synthesis in Journal of biophotonics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
57 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Intraoperative bowel perfusion assessment methods and their effects on anastomotic leak rates: meta-analysis.The British journal of surgery · 2023Pooled it
- Hyperspectral and multispectral image processing for gross-level tumor detection in skin lesions: a systematic review.Journal of biomedical optics · 2022Pooled it
- Hyperspectral Imaging and the Retina: Worth the Wave?Translational vision science & technology · 2020Pooled it
- Reconstruction Accuracy vs. Discriminative Power: Spectral Unmixing Performance in Brain Tissue Hyperspectral Imaging.Bioengineering (Basel, Switzerland) · 2026Article
- Neural illumination calibration for surgical workflow-optimized spectral imaging.International journal of computer assisted radiology and surgery · 2026Article
- From Image-Guided Surgery to Computer-Assisted Real-Time Diagnosis with Hyperspectral and Multispectral Imaging: A Systematic Review in Gynecologic Oncology.Diagnostics (Basel, Switzerland) · 2026Review
- Label tree semantic losses for rich multi-class medical image segmentation.Frontiers in artificial intelligence · 2026Article
- Hyperspectral Imaging Accurately Detects Renal Malperfusion Due to High Intrarenal Pressure.European urology open science · 2025Article
- Skin Lesion Classification in Head and Neck Cancers Using Tissue Index Images Derived from Hyperspectral Imaging.Cancers · 2025Article
- First-in-human pilot study of snapshot multispectral endoscopy for delineation of pituitary adenoma.Journal of biomedical optics · 2025Article
- LED-based, real-time, hyperspectral imaging device.Journal of medical imaging (Bellingham, Wash.) · 2025Article
- Hyperspectral abdominal laparoscopy with real-time quantitative tissue oxygenation imaging: a live porcine study.Frontiers in medical technology · 2025Article
- Transmissive-Detected Hyperspectral Imaging for Single-Vessel-Resolution Blood Oxygen Mapping.BME frontiers · 2025Article
- Introduction to the Special Issue on Molecular Guided Surgery.Journal of biomedical optics · 2025Article
- Calibration-Jitter: Augmentation of hyperspectral data for improved surgical scene segmentation.Healthcare technology letters · 2024Article
- RGB to hyperspectral: Spectral reconstruction for enhanced surgical imaging.Healthcare technology letters · 2024Article
- Article
- The Utility of Indocyanine Green Angiography in Breast Reconstruction to Detect Mastectomy Skin Flap Necrosis and Free Flap Perfusion: An Umbrella Review.Bioengineering (Basel, Switzerland) · 2024Review
- Hyperspectral imaging with deep learning for quantification of tissue hemoglobin, melanin, and scattering.Journal of biomedical optics · 2024Article
- Advancing DIEP Flap Monitoring with Optical Imaging Techniques: A Narrative Review.Sensors (Basel, Switzerland) · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
Multispectral and hyperspectral imaging (HSI) are emerging optical imaging techniques with the potential to transform the way surgery is performed but it is not clear whether current systems are capable of delivering real-time tissue characterization and surgical guidance. We conducted a systematic review of surgical in vivo label-free multispectral and HSI systems that have been assessed intraoperatively in adult patients, published over a 10-year period to May 2018. We analysed 14 studies including 8 different HSI systems. Current in-vivo HSI systems generate an intraoperative tissue oxygenation map or enable tumour detection. Intraoperative tissue oxygenation measurements may help to predict those patients at risk of postoperative complications and in-vivo intraoperative tissue characterization may be performed with high specificity and sensitivity. All systems utilized a line-scanning or wavelength-scanning method but the spectral range and number of spectral bands employed varied significantly between studies and according to the system's clinical aim. The time to acquire a hyperspectral cube dataset ranged between 5 and 30 seconds. No safety concerns were reported in any studies. A small number of studies have demonstrated the capabilities of intraoperative in-vivo label-free HSI but further work is needed to fully integrate it into the current surgical workflow.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.