Evidence map›Paper›PMID 30863429›Full record

ArticleFrontiers in genetics2019

An Exome-Wide Sequencing Study of the GOLDN Cohort Reveals Novel Associations of Coding Variants and Fasting Plasma Lipids.

Xin Geng, Marguerite R Irvin, Bertha Hidalgo, Stella Aslibekyan, Vinodh Srinivasasainagendra, Ping An, Alexis C Frazier-Wood, Hemant K Tiwari, Tushar Dave, Kathleen Ryan and 9 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 9 institutions in 3 countries.

Xin GengSchool of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, TX, United States.
Marguerite R IrvinDepartment of Epidemiology, The University of Alabama at Birmingham, Birmingham, AL, United States.
Bertha HidalgoDepartment of Epidemiology, The University of Alabama at Birmingham, Birmingham, AL, United States.
Stella AslibekyanDepartment of Epidemiology, The University of Alabama at Birmingham, Birmingham, AL, United States.
Vinodh SrinivasasainagendraDepartment of Biostatistics, The University of Alabama at Birmingham, Birmingham, AL, United States.
Ping AnDivision of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, MO, United States.
Alexis C Frazier-WoodUSDA/ARS Children's Nutrition Research Center, Baylor College of Medicine, Houston, TX, United States.
Hemant K TiwariDepartment of Biostatistics, The University of Alabama at Birmingham, Birmingham, AL, United States.
Tushar DaveDivision of Endocrinology, Diabetes and Nutrition, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, United States.
Kathleen RyanDivision of Endocrinology, Diabetes and Nutrition, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, United States.
Jose M OrdovasNutrition and Genomics Laboratory, Jean Mayer United States Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA, United States.
Robert J StrakaDepartment of Experimental and Clinical Pharmacology, University of Minnesota, Minneapolis, MN, United States.
Mary F FeitosaDivision of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, MO, United States.
Paul N HopkinsDivision of Cardiovascular Medicine, University of Utah, Salt Lake City, UT, United States.
Ingrid BoreckiGenetic Analysis Center, Department of Biostatistics, University of Washington, Seattle, WA, United States.
Michael A ProvinceDivision of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, MO, United States.
Braxton D MitchellDivision of Endocrinology, Diabetes and Nutrition, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, United States.
Donna K ArnettCollege of Public Health, University of Kentucky, Lexington, KY, United States.
Degui ZhiSchool of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, TX, United States.
University of Alabama at Birmingham · USUniversity of Maryland, Baltimore · USThe University of Texas Health Science Center at Houston · USCancer Research And Biostatistics · USChildren's Nutrition Research Center at Baylor College of Medicine · USIMDEA Food · ESUniversity of Kentucky · USUniversity of Minnesota · USUniversity of Utah · US

Funding

University of Alabama at Birmingham's Diabetes Research CenterP30DK079626 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BARBARA A GOWER · 2013 to 2026
$19.5M
HYPERGEN: GENETICS OF LEFT VENTRICULAR HYPERTROPHYR01HL055673 · NHLBI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI ARNETT, DONNA K · 1996 to 2016
$18.1M
Research BaseP30DK072488 · NIDDK · UNIVERSITY OF MARYLAND BALTIMORE · PI RYAN, ALICE S. · 2005 to 2019
$17.3M
Atherosclerosis, Plaque and CVD in CommunitiesU01HL075572 · NHLBI · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI BOERWINKLE, ERIC A · 2004 to 2007
$15.6M
Genetic and Environmental Determinants of TriglyceridesU01HL072524 · NHLBI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI ARNETT, DONNA K · 2002 to 2008
$11.9M
Genome-wide Search for CVD Gene-Environment InteractionsU01HL072515 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI SHULDINER, ALAN R. · 2002 to 2008
$11.2M
Studies of Rare Genetic Variation in the Isolated Population of SardiniaR01HL117626 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ABECASIS, GONCALO · 2013 to 2016
$10.5M
Rare variants and NHLBI traits in deeply phenotyped cohortsR01HL120393 · NHLBI · UNIVERSITY OF WASHINGTON · PI PSATY, BRUCE M, RICE, KENNETH M. · 2014 to 2016
$8.9M
Genomewide Association Study of Lipid Response to Fenofibrate and Dietary FatR01HL091357 · NHLBI · UNIVERSITY OF KENTUCKY · PI ARNETT, DONNA K · 2008 to 2018
$5.8M
Identification and Functional characterization of a gene influencing LDL-C on 5qR01HL121007 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI MITCHELL, BRAXTON D · 2014 to 2017
$3.1M
Integrative -omics study of postprandial lipoprotein phenotypesK01HL136700 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ASLIBEKYAN, STELLA · 2017 to 2018
$295k
NHLBI NIH HHS K01 HL136700NHLBI NIH HHS R01 HL055673NHLBI NIH HHS R01 HL091357NHLBI NIH HHS R01 HL117626NHLBI NIH HHS R01 HL120393NHLBI NIH HHS R01 HL121007NHLBI NIH HHS U01 HL072515NHLBI NIH HHS U01 HL072524NHLBI NIH HHS U01 HL075572NIDDK NIH HHS P30 DK072488NIDDK NIH HHS P30 DK079626
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

cholesterolepidemiologygeneticsHDLLDLrare varianttriglyceridewhole exome sequencing

Identifiers

PMID30863429
PMCPMC6399202
OpenAlexW2917670243

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.