Evidence map›Paper›PMID 30866495›Full record

SynthesisInternational journal of environmental research and public health2019

Are Office-Based Workplace Interventions Designed to Reduce Sitting Time Cost-Effective Primary Prevention Measures for Cardiovascular Disease? A Systematic Review and Modelled Economic Evaluation.

Lan Gao, Phuong Nguyen, David Dunstan, Marjory Moodie

Abstract readSystematic Review
In one paragraph

Synthesis in International journal of environmental research and public health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Modelling the potential health and economic benefits of reducing population sitting time in Australia.The international journal of behavioral nutrition and physical activity · 2022
    Trial
  2. A Cost and Cost-Benefit Analysis of the Stand More AT Work (SMArT Work) Intervention.International journal of environmental research and public health · 2020
    Trial
  3. Review
  4. Article
  5. The Cost-Effectiveness of the SMART Work & Life Intervention for Reducing Sitting Time.International journal of environmental research and public health · 2022
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Diabetes in the Workplace: Risks and Remedies.Indian journal of endocrinology and metabolism
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lan GaoDeakin Health Economics, Centre for Population Health Research, Deakin University, Geelong, VIC 3127, Australia. lan.gao@deakin.edu.au.ORCID 0000-0001-9734-1140
Phuong NguyenDeakin Health Economics, Centre for Population Health Research, Deakin University, Geelong, VIC 3127, Australia. phuong.nguyen@deakin.edu.au.
David DunstanBaker Heart and Diabetes Institute, Melbourne 3004, Australia. David.Dunstan@baker.edu.au.
Marjory MoodieDeakin Health Economics, Centre for Population Health Research, Deakin University, Geelong, VIC 3127, Australia. marj.moodie@deakin.edu.au.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo assess the cost-effectiveness of workplace-delivered interventions designed to reduce sitting time as primary prevention measures for cardiovascular disease (CVD) in Australia.

methodsA Markov model was developed to simulate the lifetime cost-effectiveness of a workplace intervention for the primary prevention of CVD amongst office-based workers. An updated systematic review and a meta-analysis of workplace interventions that aim to reduce sitting time was conducted to inform the intervention effect. The primary outcome was workplace standing time. An incremental cost-effectiveness ratio (ICER) was calculated for this intervention measured against current practice. Costs (in Australia dollars) and benefits were discounted at 3% annually. Both deterministic (DSA) and probabilistic (PSA) sensitivity analyses were performed.

resultsThe updated systematic review identified only one new study. Only the multicomponent intervention that included a sit-and-stand workstation showed statistically significant changes in the standing time compared to the control. The intervention was associated with both higher costs ($6820 versus $6524) and benefits (23.28 versus 23.27, quality-adjusted life year, QALYs), generating an ICER of $43,825/QALY. The DSA showed that target age group for the intervention, relative risk of CVD relative to the control and intervention cost were the key determinants of the ICER. The base case results were within the range of the 95% confidence interval and the intervention had a 85.2% probability of being cost-effective.

conclusionsA workplace-delivered intervention in the office-based setting including a sit-and-stand desk component is a cost-effective strategy for the primary prevention of CVD. It offers a new option and location when considering interventions to target the growing CVD burden.

Indexed as

Sitting PositionAustraliaCardiovascular DiseasesCost-Benefit AnalysisHumansMarkov ChainsModels, EconomicOccupational HealthPrimary PreventionQuality-Adjusted Life YearsStanding PositionTime FactorsWorkplacecardiovascular diseasecost-effective analysismulticomponentprimary preventionsedentary behaviourworkplace intervention

Identifiers

PMID30866495
PMCPMC6427179

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.