Evidence map›Paper›PMID 30866507›Full record

ArticleMolecules (Basel, Switzerland)2019

In Silico Methods for the Discovery of Orthosteric GABA

Linn M Evenseth, Dawid Warszycki, Andrzej J Bojarski, Mari Gabrielsen, Ingebrigt Sylte

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Interrogation ofSaudi journal of biological sciences · 2021
    Article
  4. Article
  5. The GABAMolecules (Basel, Switzerland) · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Linn M EvensethMolecular Pharmacology and Toxicology, Department of Medical Biology, Faculty of Health Sciences, UiT-The Arctic University of Norway, NO-9037 Tromsø, Norway. linn.evenseth@uit.no.
Dawid WarszyckiDepartment of Medicinal Chemistry, Institute of Pharmacology, Polish Academy of Science, Smetna 12, 31-343 Kraków, Poland. warszyc@if-pan.krakow.pl.ORCID 0000-0002-2393-4709
Andrzej J BojarskiDepartment of Medicinal Chemistry, Institute of Pharmacology, Polish Academy of Science, Smetna 12, 31-343 Kraków, Poland. bojarski@if-pan.krakow.pl.ORCID 0000-0003-1417-6333
Mari GabrielsenMolecular Pharmacology and Toxicology, Department of Medical Biology, Faculty of Health Sciences, UiT-The Arctic University of Norway, NO-9037 Tromsø, Norway. mari.gabrielsen@uit.no.
Ingebrigt SylteMolecular Pharmacology and Toxicology, Department of Medical Biology, Faculty of Health Sciences, UiT-The Arctic University of Norway, NO-9037 Tromsø, Norway. ingebrigt.sylte@uit.no.

Funding

HelseNord HNF1426-18Polish National Centre for Reserach and development LIDER/37/0137/L-9/17/NCBR/2018Polish-Norwegian research program Pol-Nor/198887/73/2013
6 · The paper itself

Abstract

The GABA

Indexed as

Computer SimulationDrug DiscoveryGABA Agentsgamma-Aminobutyric AcidHumansLigandsModels, MolecularMolecular Docking SimulationReceptors, GABA-BStructure-Activity RelationshipGABA Agentsgamma-Aminobutyric AcidLigandsReceptors, GABA-BGABAB receptorligand-based screeningorthosteric binding sitestructure-based screeningvirtual screening

Identifiers

PMID30866507
PMCPMC6429233

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.