Evidence map›Paper›PMID 30870041›Full record

ArticleExpert opinion on drug discovery2019

Are animal models a necessity for acute radiation syndrome drug discovery?

Dörthe Schaue, William H McBride

Abstract readEditorial
PubMed Full text at PMC Publisher
In one paragraph

Article in Expert opinion on drug discovery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Radiation-induced tissue damage and response.The Journal of pathology · 2020
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Dörthe Schauea Department Radiation Oncology , University of California at Los Angeles , Los Angeles , CA , USA.
William H McBridea Department Radiation Oncology , University of California at Los Angeles , Los Angeles , CA , USA.

Funding

UCLA Center for Biological RadioprotectorsU19AI067769 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI CHUTE, JOHN P, MCBRIDE, WILLIAM H. · 2005 to 2019
$44.6M
Myeloid reprogramming in response to acute radiation tissue damageR01CA226875 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI SCHAUE, DORTHE · 2019 to 2023
$1.8M
Radiotherapy-induced tumor immunityR01CA191234 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI SCHAUE, DORTHE · 2015 to 2019
$1.8M
NCI NIH HHS R01 CA191234NCI NIH HHS R01 CA226875NIAID NIH HHS U19 AI067769
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Acute Radiation SyndromeAnimalsDrug DiscoveryHumansModels, AnimalRadiation-Protective AgentsRadiation-Protective AgentsAcute radiation syndromesanimal modelsradiation mitigation

Identifiers

PMID30870041
PMCPMC6497543

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.