Evidence map›Paper›PMID 30872841›Full record

ArticleAIChE journal. American Institute of Chemical Engineers2018

Coupling Brain Perfusion Screens and Next Generation Sequencing to Identify Blood-Brain Barrier Binding Antibodies.

C Christopher Stutz, Julia V Georgieva, Eric V Shusta

Abstract read
In one paragraph

Article in AIChE journal. American Institute of Chemical Engineers, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Frontiers in microbiology · 2022
    Review
  5. Article
  6. Article
  7. Antibody screening using a human iPSC-based blood-brain barrier model identifies antibodies that accumulate in the CNS.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2020
    Article
  8. Review
  9. Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

C Christopher StutzDept. of Chemical and Biological Engineering, University of Wisconsin-Madison, Madison, WI 53706.
Julia V GeorgievaDept. of Chemical and Biological Engineering, University of Wisconsin-Madison, Madison, WI 53706.
Eric V ShustaDept. of Chemical and Biological Engineering, University of Wisconsin-Madison, Madison, WI 53706.

Funding

Identification of Lamprey Antibodies Capable of Noninvasive Brain Drug DeliveryR01NS099158 · NINDS · UNIVERSITY OF WISCONSIN-MADISON · PI SHUSTA, ERIC V · 2017 to 2021
$1.7M
Proteomic Evaluation of the Blood-Brain Barrier Receptor-Mediated TransportomeR01NS071513 · NINDS · UNIVERSITY OF WISCONSIN-MADISON · PI SHUSTA, ERIC V · 2010 to 2013
$1.1M
NINDS NIH HHS R01 NS071513NINDS NIH HHS R01 NS099158
6 · The paper itself

Abstract

Antibodies that target the blood-brain barrier (BBB)

Identifiers

PMID30872841
PMCPMC6411078

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.