Evidence map›Paper›PMID 30885998›Full record

ArticleBlood advances2019

Effect of chronic opioid therapy on pain and survival in a humanized mouse model of sickle cell disease.

Huy Tran, Varun Sagi, Waogwende Leonce Song-Naba, Ying Wang, Aditya Mittal, Yann Lamarre, Lei Zhang, Kalpna Gupta

Abstract read
In one paragraph

Article in Blood advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Observational
  4. Review
  5. Review
  6. Article
  7. Pain in sickle cell disease: current and potential translational therapies.Translational research : the journal of laboratory and clinical medicine · 2021
    Review
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Huy TranVascular Biology Center, Division of Hematology, Oncology and Transplantation, Department of Medicine, and.
Varun SagiVascular Biology Center, Division of Hematology, Oncology and Transplantation, Department of Medicine, and.
Waogwende Leonce Song-NabaVascular Biology Center, Division of Hematology, Oncology and Transplantation, Department of Medicine, and.
Ying WangVascular Biology Center, Division of Hematology, Oncology and Transplantation, Department of Medicine, and.
Aditya MittalVascular Biology Center, Division of Hematology, Oncology and Transplantation, Department of Medicine, and.
Yann LamarreVascular Biology Center, Division of Hematology, Oncology and Transplantation, Department of Medicine, and.
Lei ZhangBiostatistical Design and Analysis Center, Clinical and Translational Sciences Institute, University of Minnesota, Minneapolis, MN.
Kalpna GuptaVascular Biology Center, Division of Hematology, Oncology and Transplantation, Department of Medicine, and.

Funding

University of Minnesota Clinical and Translational Science Institute (UMN CTSI)UL1TR000114 · NCATS · UNIVERSITY OF MINNESOTA · PI BLAZAR, BRUCE R · 2012 to 2015
$35.0M
Cannabinoid-based therapy and approaches to quantify pain in sickle cell diseaseU01HL117664 · NHLBI · UNIVERSITY OF MINNESOTA · PI GUPTA, KALPNA · 2013 to 2018
$9.6M
NCATS NIH HHS UL1 TR000114NHLBI NIH HHS U01 HL117664
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Survival RateAnalgesics, OpioidAnemia, Sickle CellAnimalsFemaleHumansHyperalgesiaMaleMiceMorphinePainAnalgesics, OpioidMorphine

Identifiers

PMID30885998
PMCPMC6436015

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.