ArticleFrontiers in psychiatry2019
Decreased Response to Positive Facial Affect in a Depressed Cohort in the Dorsal Striatum During a Working Memory Task-A Preliminary fMRI Study.
Article in Frontiers in psychiatry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Meta-analysis of neural correlates of working memory, reward, and emotion processing in major depressive disorder using AES-SDM.BMC psychiatry · 2026Pooled it
- Meta-analysis of neural correlates of working memory, reward, and emotion processing in major depressive disorder using ALE.Psychological medicine · 2026Pooled it
- Modulated theta band frequency with binaural beat stimulation correlates with improved cognitive scores in Alzheimer's patients.Frontiers in aging neuroscience · 2025Article
- Psychiatric Characteristics, Symptoms of Insomnia and Depression, Emotion Regulation, and Social Activity among Swiss Medical Students.Journal of clinical medicine · 2024Article
- Cilia in the Striatum Mediate Timing-Dependent Functions.Molecular neurobiology · 2023Article
- Distinct Effects of Anxiety and Depression on Updating Emotional Information in Working Memory.International journal of environmental research and public health · 2022Article
- Bias of Attentional Oscillations in Individuals with Subthreshold Depression: Evidence from a Pre-Cueing Facial Expression Judgment Task.International journal of environmental research and public health · 2022Article
- Individuals with Major Depressive Disorder Report High Scores of Insecure-Avoidant and Insecure-Anxious Attachment Styles, Dissociative Identity Symptoms, and Adult Traumatic Events.Healthcare (Basel, Switzerland) · 2021Article
- Emotional Contagion: A Brief Overview and Future Directions.Frontiers in psychology · 2021Review
- Event-Related Potential to Conscious and Nonconscious Emotional Face Perception in Females with Autistic-Like Traits.Journal of clinical medicine · 2020Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
People with depression have shown alterations in processing emotional information and working memory functionality. There is some evidence that emotional content may interact with working memory update processes, however neurological correlates are current unknown. In this preliminary study we utilized a novel version of the emotional variant of the n-back working memory task in fMRI. We examined BOLD response of 14 healthy controls and 13 depressed participants in response to happy, sad, and neutral displays of facial affect. No accuracy or reaction time differences were found between the two groups. The depressed group showed significantly decreased BOLD response to happy faces compared to the control group areas of the dorsal striatum and anterior cingulate. Significant, moderate, positive associations were found between right caudate activation with anxiety score and anterior cingulate activation with depression score in those with depression. Our novel task was able to elicit group level differences in emotional processing during working memory update. These results suggest those with depression fail to differentiate between positive emotional stimuli and stimuli with no emotional content.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.