ArticleAmerican journal of physiology. Regulatory, integrative and comparative physiology2019
Two nights of recovery sleep restores the dynamic lipemic response, but not the reduction of insulin sensitivity, induced by five nights of sleep restriction.
Article in American journal of physiology. Regulatory, integrative and comparative physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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Who cites it
23 citing papers in PubMed.
- Insufficient sleep and weekend recovery sleep: classification by a metabolomics-based machine learning ensemble.Scientific reports · 2023Trial
- Four nights of sleep restriction suppress the postprandial lipemic response and decrease satiety.Journal of lipid research · 2019Trial
- From yawn to dawn: the effects of a sleep extension intervention on objective and subjective dimensions of sleep health in adults with habitual short sleep duration.Sleep advances : a journal of the Sleep Research Society · 2026Article
- Weekend catch-up sleep is associated with a decreased risk of kidney disease in American adults: an analysis of NHANES 2017-2020.International urology and nephrology · 2025Article
- Nonlinear association between weekend sleep recovery (WSR) and insulin resistance: benefits in males and short weekday sleepers.Endocrine connections · 2025Article
- Association of Weekend Catch-Up Sleep With the Triglyceride/High-Density Lipoprotein Cholesterol Ratio.Cureus · 2025Article
- The Impact of Weekend Catch-up Sleep on Hepatic Steatosis among Adults in the United States.International journal of medical sciences · 2025Article
- Sleep extension and cardiometabolic health: what it is, possible mechanisms and real-world applications.The Journal of physiology · 2024Review
- Sleep Debt and Insulin Resistance: What's Worse, Sleep Deprivation or Sleep Restriction?Sleep science (Sao Paulo, Brazil) · 2024Article
- Catch-up sleep on free days and body mass index: results from the seventh Korea National Health and Nutrition Examination Survey, 2016.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2024Article
- Performance of an open machine learning model to classify sleep/wake from actigraphy across ∼24-hour intervals without knowledge of rest timing.Sleep health · 2023Article
- Effect of weekend catch-up sleep on high-sensitivity C-reactive protein levels according to bedtime inconsistency: a population-based cross-sectional study.Scientific reports · 2022Article
- Associations Between Sleep and Metabolic Outcomes in Preadolescent Children.Journal of the Endocrine Society · 2022Article
- Effects of sleep deprivation on coronary heart disease.The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2022Review
- Does Insufficient Sleep Increase the Risk of Developing Insulin Resistance: A Systematic Review.Cureus · 2022Review
- Article
- The Effect of Sleep Restriction, With or Without Exercise, on Skeletal Muscle Transcriptomic Profiles in Healthy Young Males.Frontiers in endocrinology · 2022Article
- Modest sleep restriction does not influence steps, physical activity intensity or glucose tolerance in obese adults.Journal of sleep research · 2021Article
- Plasma Free Fatty Acid Concentration as a Modifiable Risk Factor for Metabolic Disease.Nutrients · 2021Review
- A Model of Adolescent Sleep Health and Risk for Type 2 Diabetes.Current diabetes reports · 2021Review
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Chronic inadequate sleep is associated with increased risk of cardiometabolic diseases. The mechanisms involved are poorly understood but involve changes in insulin sensitivity, including within adipose tissue. The aim of this study was to assess the effects of sleep restriction on nonesterified fatty acid (NEFA) suppression profiles in response to an intravenous glucose tolerance test (IVGTT) and to assess whether 2 nights of recovery sleep (a "weekend") is sufficient to restore metabolic health. We hypothesized that sleep restriction impairs both glucose and lipid metabolism, specifically adipocyte insulin sensitivity, and the dynamic lipemic response of adipocyte NEFA release during an IVGTT. Fifteen healthy men completed an inpatient study of 3 baseline nights (10 h of time in bed/night), followed by 5 nights of 5 h of time in bed/night and 2 recovery nights (10 h of time in bed/night). IVGTTs were performed on the final day of each condition. Reductions in insulin sensitivity without a compensatory change in acute insulin response to glucose were consistent with prior studies (insulin sensitivity
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.