Evidence map›Paper›PMID 30903807›Full record

ArticleBosnian journal of basic medical sciences2019

Histological and biochemical effects of Cinnamomum cassia nanoparticles in kidneys of diabetic Sprague-Dawley rats.

Koffi Kouame, Aniekan Imo Peter, Edidiong Nnamso Akang, Roshila Moodley, Edwin Coleridge Naidu, Onyemaechi Okpara Azu

Open access · diamondAbstract read
In one paragraph

Article in Bosnian journal of basic medical sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Review
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  10. Article
  11. Review
  12. Evaluation of Preclinical and Clinical Studies Published in Medical Journals of Bosnia and Herzegovina: Methodology Issues.Acta informatica medica : AIM : journal of the Society for Medical Informatics of Bosnia & Herzegovina : casopis Drustva za medicinsku informatiku BiH · 2020
    Article
  13. Molecules (Basel, Switzerland) · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Koffi KouameDiscipline of Clinical Anatomy, School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban, South Africa. kouamek9@gmail.com.
Aniekan Imo Peter
Edidiong Nnamso Akang
Roshila Moodley
Edwin Coleridge Naidu
Onyemaechi Okpara Azu
University of KwaZulu-Natal · ZAUniversity of Lagos · NGUniversity of Namibia · NA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study investigated the antidiabetic activity of Cinnamomum cassia (C. cassia, Cc) silver nanoparticles (CcAgNPS) and effects of C. cassia on the kidneys of rats with induced type 2 diabetes. Twenty-four Sprague-Dawley rats weighing 250 ± 20 g were induced with diabetes by intraperitoneal injection of streptozotocin (STZ, 60 mg/kg). Animals were randomly assigned to one of four groups (n = 6) and treated for eight weeks with normal saline (control, group A), 5 mg/kg of CcAgNPs (group B), 10 mg/kg of CcAgNPs (group C), or 200 mg/kg of Cc (group D). Body weight and fasting blood glucose (FBG) was measured weekly and fortnightly, respectively. At the end of experiments animals were euthanized, blood and kidney tissue samples were collected for biochemistry (oxidative stress markers and renal function parameters) and kidneys were harvested for histology (PAS and H.

Indexed as

AnimalsBlood GlucoseBody WeightCinnamomum aromaticumCreatinineDiabetes Mellitus, ExperimentalDiabetes Mellitus, Type 2GlutathioneHypoglycemic AgentsKidneyMaleMetal NanoparticlesOxidative StressPlant ExtractsPowdersRatsBlood GlucoseCreatinineGlutathioneHypoglycemic AgentsPlant ExtractsPowdersSilverStreptozocin

Identifiers

PMID30903807
PMCPMC6535384
OpenAlexW3022980799

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.