ArticleBMJ open2019
Childhood maltreatment and biomarkers for cardiometabolic disease in mid-adulthood in a prospective British birth cohort: associations and potential explanations.
Article in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 26 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.
- Sexual violence and cardiovascular disease risk: A systematic review and meta-analysis.Maturitas · 2021Pooled it
- Associations between childhood maltreatment and mid-life health risks and risky health behaviors in a nationally representative sample.SSM. Mental health · 2026Article
- Childhood maltreatment and cognitive functioning from young adulthood to late midlife: A prospective study.Neuropsychology · 2026Article
- Childhood maltreatment confers long-term risk for cognitive impairment: A prospective investigation.The journal of prevention of Alzheimer's disease · 2025Article
- Lifetime Exposure to Violence and Early Cardiometabolic Risk Factors in a Healthy Swedish Cohort.Journal of the American Heart Association · 2025Article
- Exposure to abuse and changes in cardiometabolic risk profiles over 3 years in young South African women.BMC public health · 2025Article
- Proposed Physiological Mechanisms Underlying the Association between Adverse Childhood Experiences and Mental Health Conditions: A Narrative Review.Children (Basel, Switzerland) · 2024Review
- Childhood maltreatment and health in the UK Biobank: triangulation of outcome-wide and polygenic risk score analyses.BMC medicine · 2024Article
- Influencing Factors of Healthy Aging Risk Assessed Using Biomarkers: A Life Course Perspective.China CDC weekly · 2024Article
- Childhood sexual abuse and pervasive problems across multiple life domains: Findings from a five-decade study.Development and psychopathology · 2024Article
- Adverse Childhood Experiences and BMI: Lifecourse Associations in a Black-White U.S. Women Cohort.American journal of preventive medicine · 2024Article
- Child Maltreatment and Metabolic Syndrome: A Systematic Review.Diabetes, metabolic syndrome and obesity : targets and therapy · 2024Review
- Association of adverse childhood experiences with lipid profiles and atherogenic risk indices in a middle-to-older aged population.SSM - population health · 2023Article
- Investigating effect modification between childhood maltreatment and genetic risk for cardiovascular disease in the UK Biobank.PloS one · 2023Article
- Associations of abuse and neglect with young adult health in a population-based longitudinal cohort: Findings from Project EAT.Preventive medicine · 2022Article
- Childhood adversity and cardiometabolic biomarkers in mid-adulthood in the 1958 British birth cohort.SSM - population health · 2022Article
- Associations Between Child Maltreatment, Inflammation, and Comorbid Metabolic Syndrome to Depressed Mood in a Multiethnic Urban Population: The HELIUS Study.Frontiers in psychology · 2022Article
- Abuse in Childhood and Cardiometabolic Health in Early Adulthood: Evidence From the Avon Longitudinal Study of Parents and Children.Journal of the American Heart Association · 2021Article
- Mitochondria and early-life adversity.Mitochondrion · 2021Article
- Psychological Factors as Determinants of Chronic Conditions: Clinical and Psychodynamic Advances.Frontiers in psychology · 2021Article
Corrections and comments
- Erratum issuedCorrection:2019
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
objectivesResearch on associations between childhood maltreatment and adult cardiometabolic disease risk is sparse. We aimed to investigate associations between different forms of child maltreatment and mid-adult cardiometabolic markers and whether potential intermediaries could account for the associations observed.
setting1958 British birth cohort.
participantsApproximately 9000 cohort members with data on cardiometabolic markers. OUTCOMES: Adult (45y) cardiometabolic markers (blood pressure, lipids and glycated haemoglobin [HbA
resultsSeventeen per cent of participants were identified as neglected; 6.1%, 1.6% and 10.0% were identified as experiencing physical, sexual and psychological abuse, respectively. Childhood neglect and physical abuse were associated with high body mass index (BMI) and large waist circumference when adjusting for early-life covariates. For neglect, the adjusted odds ratio (AOR) was 1.16 (95% CI: 1.02 to 1.32) and 1.15 (1.02 to 1.30) for general and central obesity, respectively, and for physical abuse, the respective AOR was 1.36 (1.13 to 1.64) and 1.38 (1.16 to 1.65). Neglect was also associated with raised triglycerides by 3.9 (0.3 to 7.5)% and HbA
conclusionsChildhood maltreatments, particularly neglect and physical abuse, were associated with greater adiposity and poorer lipid and HbA
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.