Evidence map›Paper›PMID 30909019›Full record

ArticleDrug and alcohol dependence2019

Unintentional drug overdose deaths involving cocaine among middle-aged and older adults in New York City.

Benjamin H Han, Ellenie Tuazon, Hillary V Kunins, Shivani Mantha, Denise Paone

Open access · greenAbstract read
In one paragraph

Article in Drug and alcohol dependence, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 30 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Benjamin H HanDivision of Geriatric Medicine and Palliative Care, New York University School of Medicine, United States. Electronic address: Benjamin.Han@nyumc.org.
Ellenie TuazonNew York City Department of Health and Mental Hygiene, United States.
Hillary V KuninsNew York City Department of Health and Mental Hygiene, United States.
Shivani ManthaNew York City Department of Health and Mental Hygiene, United States.
Denise PaoneNew York City Department of Health and Mental Hygiene, United States.
New York City Department of Health and Mental Hygiene · USNew York University · US

Funding

Chronic Disease and Health Outcomes of Older Adults with Opioid Use DisordersK23DA043651 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI HAN, BENJAMIN HYUN · 2018 to 2023
$1.2M
NIDA NIH HHS K23 DA043651
6 · The paper itself

Abstract

backgroundCocaine is commonly involved in unintentional drug poisoning (overdose) deaths, accounting for 46% of overdose deaths in New York City (NYC) in 2016. However, little research exists regarding cocaine use by middle-aged and older adults, who are more likely than younger individuals to have underlying cardiovascular disease (CVD) and therefore, may be at increased risk for the adverse health consequences of cocaine.

methodsWe conducted a retrospective analysis of unintentional drug overdose deaths of middle-aged and older NYC residents age 45-84 from 2000 to 2016 using two linked sources, NYC death certificates and toxicology results from the Office of the Chief Medical Examiner.

resultsFrom 2000 to 2016, there were 6061 unintentional drug overdose deaths among New Yorkers age 45-84. Of those, cocaine was involved in 53% (n = 3183). Co-occurring opioid involvement (fentanyl, heroin, methadone, or opioid analgesics) among deaths involving cocaine was common (58%). Compared to decedents of non-cocaine involved overdose, decedents of cocaine-involved overdose were more likely to be male and non-Latino Black. Multivariable analysis showed that adults age 45-54 (adjusted odds ratio [AOR] = 1.34, 95% 1.05, 1.70), males (AOR = 1.30, 95% CI 1.15, 1.46), Bronx residence (AOR = 1.29, 95% CI 1.08, 1.54), and non-Latino black race/ethnicity (AOR = 2.37, 95% CI 2.07, 2.72) were independently associated with cocaine-involved overdose.

conclusionCharacteristics of decedents of cocaine-involved overdose overlap with populations with high CVD burden in NYC. Studies are needed to better understand the risks of cocaine among adults with underlying CVD.

Indexed as

AgedAged, 80 and overAnalgesics, OpioidCocaineCocaine-Related DisordersDeath CertificatesDrug OverdoseEthnicityFemaleHumansMaleMiddle AgedNew York CityOdds RatioRetrospective StudiesAnalgesics, OpioidCocaineCocaineMiddle-agedOlder adultsOverdose

Identifiers

PMID30909019
PMCPMC6467745
OpenAlexW2921485662

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.