Evidence map›Paper›PMID 30912633›Full record

SynthesisJBRA assisted reproduction2019

Pregnancy rates from natural and artificial cycles of women submitted to frozen embryo transfers: a metanalysis.

Karine Queiroz Poletto, Mayana de Pina Lobo, Melissa Giovanucci, Mário Silva Approbato, Eduardo Camelo de Castro

Open access · greenAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in JBRA assisted reproduction, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Karine Queiroz PolettoLaboratorio de Reprodução Humana (LabRep) / FM / HC - Federal University of Goiás - Brazil.
Mayana de Pina LoboPontifical Catholic University of Goiás - Brazil.
Melissa GiovanucciPontifical Catholic University of Goiás - Brazil.
Mário Silva ApprobatoLaboratorio de Reprodução Humana (LabRep) / FM / HC - Federal University of Goiás - Brazil.
Eduardo Camelo de CastroLaboratorio de Reprodução Humana (LabRep) / FM / HC - Federal University of Goiás - Brazil.
Universidade Federal de Goiás · BRPontifícia Universidade Católica de Goiás · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo compare pregnancy rates from natural and artificial cycles of women submitted to frozen embryo transfers.

methodsA systematic review was performed by PubMed search using the following algorithm: (endometrial [All Fields] AND preparation [All Fields]) AND (("freezing"[MeSH Terms] OR "freezing"[All Fields] OR "frozen"[All Fields]) AND thawed [All Fields]) and (natural cycles) AND (artificial cycle). Inclusion criteria: prospective and retrospective cohort studies. Exclusion criteria: use of hCG in the natural cycle, oocyte donors, and use of disused freezing techniques. Data were analyzed with the SPSS v.23 software and with a significance level of 5%. The meta-analysis was performed with RevMan 5.3 software. I² was calculated.

results709 papers were retrieved. Five studies fulfilled the inclusion and exclusion criteria. From these studies, we analyzed 8,968 natural or artificial cycles. A contingency table compared the results of the natural and artificial cycles and the number of clinical pregnancies obtained in each selected paper. The I

conclusionThere is insufficient scientific evidence to state that the artificial cycle yields better pregnancy rates than the natural cycle in women submitted to frozen embryo transfer. Limitations of this study include a small number of papers and heterogeneity among the studies.

Indexed as

Pregnancy RateAdultCryopreservationEmbryo, MammalianEmbryo TransferFemaleFreezingHumansMenstrual CycleOvulationOvulation InductionPregnancyReproductive Techniques, Assistedcryopreservationendometriumpregnancy rate

Identifiers

PMID30912633
PMCPMC6724391
OpenAlexW2980146875

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.