Evidence mapPaperPMID 30922244Full record

SynthesisBMC pregnancy and childbirth2019

Maternal body mass index and risk of neonatal adverse outcomes in China: a systematic review and meta-analysis.

Lei Liu, Yanan Ma, Ningning Wang, Wenjing Lin, Yang Liu, Deliang Wen

Open access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in BMC pregnancy and childbirth, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 77 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
77citing papers in PubMed, 8 pooled it
15.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

77 citing papers in PubMed, 8 syntheses or guidelines pooled it, 148 citations in OpenAlex.

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  9. Maternal mid-upper arm circumference to predict small for gestational age: Findings in a Zambian cohort.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2023
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  13. Impact of maternal health on neonatal and long-term kidney outcomes.Pediatric nephrology (Berlin, Germany) · 2026
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17 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Lei LiuSchool of Public Health, Dalian Medical University, Dalian, Liaoning Province, 116044, People's Republic of China.
Yanan MaSchool of Public Health, China Medical University, No.77 Puhe Road, Shenyang North New Area, Shenyang, Liaoning Province, 110122, People's Republic of China.
Ningning WangSchool of Public Health, Dalian Medical University, Dalian, Liaoning Province, 116044, People's Republic of China.
Wenjing LinSchool of Public Health, Dalian Medical University, Dalian, Liaoning Province, 116044, People's Republic of China.
Yang LiuSchool of Public Health, China Medical University, No.77 Puhe Road, Shenyang North New Area, Shenyang, Liaoning Province, 110122, People's Republic of China.
Deliang WenSchool of Public Health, China Medical University, No.77 Puhe Road, Shenyang North New Area, Shenyang, Liaoning Province, 110122, People's Republic of China. dlwen@cmu.edu.cn.ORCID http://orcid.org/0000-0002-4038-3849
Dalian Medical University · CNChina Medical University · CNShenyang Medical College · CN

Funding

Liaoning Distinguished Professor Liao taught (2013) No.204National Natural Science Foundation of China 71774173
6 · The paper itself

Abstract

backgroundMaternal body mass index is linked to short- and long-term unfavorable health outcomes both for child and mother. We conducted a systematic review and meta-analysis of population-based cohort studies to evaluate maternal BMI and the risk of harmful neonatal outcomes in China.

methodsSix databases identified 2454 articles; 46 met the inclusion criteria for this study. The dichotomous data on maternal BMI and harmful neonatal outcomes were extracted. Pooled statistics (odds ratios, ORs) were derived from Stata/SE, ver. 12.0. Sensitivity analyses assessed the robustness of the results. Meta-regression and subgroup meta-analyses explored heterogeneity.

resultsThe meta-analysis revealed that compared with normal BMI, high maternal BMI is associated with fetal overgrowth, defined as macrosomia ≥4000 g (OR 1.91, 95% CI 1.75-2.09); birth weight ≥ 90% for gestational age (OR 1.88, 95% CI 1.64-2.15); and increased risk of premature birth (OR 1.38, 95% CI 1.25-2.52) and neonatal asphyxia (OR 1.74, 95% CI 1.39-2.17). Maternal underweight increased the risk of low birth weight (OR 1.61, 95% CI 1.33-1.93) and small for gestational age (OR 1.75, 95% CI 1.51-2.02).

conclusionsRaised as well as low pre-pregnancy BMI is associated with adverse neonatal outcomes. Management of weight during pregnancy might help reduce their adverse neonatal outcomes in future intervention studies or programmes.

Indexed as

Body Mass IndexAdultBirth WeightChinaFemaleFetal MacrosomiaGestational Weight GainHumansInfant, Low Birth WeightInfant, NewbornInfant, Small for Gestational AgeObesityPregnancyPregnancy ComplicationsPregnancy OutcomeRisk FactorsCohort studyMaternal BMIMeta-analysisNeonatal outcomes

Identifiers

PMID30922244
PMCPMC6440121
OpenAlexW2947342046

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.