Evidence map›Paper›PMID 30924075›Full record

ReviewMolecular neurobiology2019

Arginine Vasopressin and Posterior Reversible Encephalopathy Syndrome Pathophysiology: the Missing Link?

Bérenger Largeau, Olivier Le Tilly, Bénédicte Sautenet, Charlotte Salmon Gandonnière, Chantal Barin-Le Guellec, Stephan Ehrmann

Abstract readReview
PubMed Publisher
In one paragraph

Review in Molecular neurobiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.

  1. Pooled it
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  4. Posterior reversible encephalopathy syndrome due to pituitrin for bronchiectasis with hemoptysis--a case report.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Bérenger LargeauCHRU de Tours, Laboratoire de Biochimie et Biologie Moléculaire, Tours, France. berenger.largeau@etu.univ-tours.fr.ORCID http://orcid.org/0000-0002-6824-7283
Olivier Le TillyCHRU de Tours, Laboratoire de Biochimie et Biologie Moléculaire, Tours, France.ORCID http://orcid.org/0000-0001-9308-4933
Bénédicte SautenetUniversité de Tours, Université de Nantes, INSERM, Methods in patients-centered outcomes and health research (SPHERE) - UMR 1246, CHRU de Tours, Service de Néphrologie-Hypertension artérielle, Dialyses et Transplantation Rénale, Tours, France.ORCID http://orcid.org/0000-0001-8430-4543
Charlotte Salmon GandonnièreCHRU de Tours, Service de Médecine Intensive Réanimation, Tours, France.ORCID http://orcid.org/0000-0001-7675-9564
Chantal Barin-Le GuellecUniversité de Tours, Université de Limoges, INSERM, Individual profiling and prevention of risks with immunosuppressive therapies and transplantation (IPPRITT) - UMR 1248, CHRU de Tours, Laboratoire de Biochimie et Biologie Moléculaire, Tours, France.ORCID http://orcid.org/0000-0001-5846-8616
Stephan EhrmannUniversité de Tours, INSERM, Centre d'étude des pathologies respiratoires (CEPR) - UMR 1100, CHRU de Tours, Service de Médecine Intensive Réanimation, CIC 1415, réseau CRICS-TRIGGERSEP, Tours, France.ORCID http://orcid.org/0000-0001-6221-4467
Université de Tours · FRCentre Hospitalier Universitaire de Tours · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Posterior reversible encephalopathy syndrome (PRES) is a clinicoradiological entity characterized by a typical brain edema. Its pathogenesis is still debated through hypoperfusion and hyperperfusion theories, which have many limitations. As PRES occurs almost exclusively in clinical situations with arginine vasopressin (AVP) hypersecretion, such as eclampsia and sepsis, we hypothesize that AVP plays a central pathophysiologic role. In this review, we discuss the genesis of PRES and its symptoms through this novel approach. We theorize that AVP axis stimulation precipitates PRES development through an increase in AVP secretion or AVP receptor density. Activation of vasopressin V

Indexed as

AnimalsArginine VasopressinBiomarkersComorbidityDisease SusceptibilityHumansModels, BiologicalPosterior Leukoencephalopathy SyndromeArginine VasopressinBiomarkersAntidiuretic hormoneBlood-brain barrierHypertensive encephalopathyLeukoencephalopathy syndromeNeurological adverse drug reactions

Identifiers

PMID30924075
OpenAlexW2932426475

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.