Evidence map›Paper›PMID 30934642›Full record

ArticleGenes2019

Golgi Oncoprotein

Beatriz Peñalver-González, Jon Vallejo-Rodríguez, Gartze Mentxaka, Asier Fullaondo, Ainhoa Iglesias-Ara, Seth J Field, Ana M Zubiaga

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genes, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. [Golgi phosphoprotein 3 overexpression inhibits paclitaxel-induced apoptosis in HeLa cells by promoting autophagy].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2019
    Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Beatriz Peñalver-GonzálezDepartment of Genetics, Physical Anthropology and Animal Physiology, University of the Basque Country UPV/EHU, 48080 Bilbao, Spain. beatriz.penalver@ehu.eus.
Jon Vallejo-RodríguezDepartment of Genetics, Physical Anthropology and Animal Physiology, University of the Basque Country UPV/EHU, 48080 Bilbao, Spain. jon.vallejo@ehu.eus.
Gartze MentxakaDepartment of Genetics, Physical Anthropology and Animal Physiology, University of the Basque Country UPV/EHU, 48080 Bilbao, Spain. gartze.mentxaka@ehu.eus.
Asier FullaondoDepartment of Genetics, Physical Anthropology and Animal Physiology, University of the Basque Country UPV/EHU, 48080 Bilbao, Spain. asier.fullaondo@ehu.eus.ORCID 0000-0001-5387-4762
Ainhoa Iglesias-AraDepartment of Genetics, Physical Anthropology and Animal Physiology, University of the Basque Country UPV/EHU, 48080 Bilbao, Spain. ainhoa.iglesias@ehu.eus.
Seth J FieldDivision of Endocrinology and Metabolism, University of California, San Diego, La Jolla, CA 92093, USA. sjfield@ucsd.edu.
Ana M ZubiagaDepartment of Genetics, Physical Anthropology and Animal Physiology, University of the Basque Country UPV/EHU, 48080 Bilbao, Spain. ana.zubiaga@ehu.es.ORCID 0000-0002-2132-9708
University of the Basque Country · ESUniversity of California San Diego · US

Funding

GOLPH3 Pathway Regulation of Golgi Structure and FunctionR01GM120055 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FIELD, SETH J · 2016 to 2019
$1.3M
High Throughput Screen to Identify Inhibitors of the Golgi GOLPH3 PathwayR01CA201303 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FIELD, SETH J · 2016 to 2018
$1.2M
NCI NIH HHS R01 CA201303NIGMS NIH HHS R01 GM120055
6 · The paper itself

Abstract

The Golgi organelle duplicates its protein and lipid content to segregate evenly between two daughter cells after mitosis. However, how Golgi biogenesis is regulated during interphase remains largely unknown. Here we show that messenger RNA (mRNA) expression of

Indexed as

Activating Transcription Factor 2AnimalsBinding SitesCell CycleCell Line, TumorE2F Transcription FactorsGene Expression RegulationGolgi ApparatusHumansMembrane ProteinsMiceMutationNIH 3T3 CellsPhosphoproteinsPromoter Regions, GeneticActivating Transcription Factor 2E2F Transcription FactorsGOLPH3 protein, humanGPP34 protein, mouseMembrane ProteinsPhosphoproteinscell cycleCREB/ATFE2F factorsgene regulationGolgiGOLPH3

Identifiers

PMID30934642
PMCPMC6471639
OpenAlexW2924698374

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.