Evidence map›Paper›PMID 30937638›Full record

ArticleClinical rheumatology2019

Cardiac and cardiovascular morbidities in patients with psoriatic arthritis: a population-based case control study.

Adi Kibari, Arnon D Cohen, Tal Gazitt, Haim Bitterman, Idit Lavi, Ilan Feldhamer, Guy Shalom, Sari Greenberg-Dotan, Devy Zisman

Abstract read
PubMed Publisher
In one paragraph

Article in Clinical rheumatology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

  1. Pooled it
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  8. Metabolic Syndrome and Its Components in Psoriatic Arthritis.Open access rheumatology : research and reviews · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Adi KibariRheumatology Unit, Carmel Medical Center, 7 Michal Street, 34362, Haifa, Israel.
Arnon D CohenChief Physician's Office, Central Headquarters, Clalit Health Services, Tel Aviv, Israel.
Tal GazittRheumatology Unit, Carmel Medical Center, 7 Michal Street, 34362, Haifa, Israel.
Haim BittermanChief Physician's Office, Central Headquarters, Clalit Health Services, Tel Aviv, Israel.
Idit LaviDepartment of Community Medicine and Epidemiology, Carmel Medical Center, Haifa, Israel.
Ilan FeldhamerChief Physician's Office, Central Headquarters, Clalit Health Services, Tel Aviv, Israel.
Guy ShalomChief Physician's Office, Central Headquarters, Clalit Health Services, Tel Aviv, Israel.
Sari Greenberg-DotanChief Physician's Office, Central Headquarters, Clalit Health Services, Tel Aviv, Israel.
Devy ZismanRheumatology Unit, Carmel Medical Center, 7 Michal Street, 34362, Haifa, Israel. devyzisman@gmail.com.ORCID http://orcid.org/0000-0003-0523-2292
Carmel Medical Center · ILClalit Health Services · ILBen-Gurion University of the Negev · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess the prevalence of risk factors associated with cardiovascular disease (CVD) and CVD-related morbidity in a large Middle-Eastern psoriatic arthritis (PsA) cohort.

methodA retrospective case control study was conducted using Israel's largest health care provider's patient database from 2000 to 2013. For each patient with PsA, 10 patients with no history of psoriasis or arthritis were matched for age and sex. Analysis of CVD-related risk factors and morbidity included hypertension (HTN), hyperlipidemia (HLD), diabetes mellitus type 2 (DM-2), obesity, smoking, ischemic heart disease (IHD), congestive heart failure (CHF), cerebrovascular accident (CVA), carotid artery disease, peripheral vascular disease (PVD), aortic aneurism, valvular heart disease (VHD), and cardiomyopathy. Statistical analysis was conducted using t test and chi-square tests as appropriate. Univariate and multivariable logistic regression models assessed the association between PsA and CVD-related risk factors and morbidity.

resultsThree thousand one hundred sixty-one PsA patients were included, with average age 58 ± 15.0 years, of whom 53.4% were women. Increased prevalence of DM-2, HLD, HTN, and obesity (OR 1.7, 1.5, 1.5, 1.5 respectively) was noted in the PsA group. Increased prevalence of IHD (p < 0.0001), PVD (p < 0.0001), CHF (p = 0.002), VHD (p < 0.0001), and cardiomyopathy (p = 0.006) was found in the PsA group compared to the control group even after adjusting for CVD risk factors.

conclusionsA high prevalence of CVD-related risk factors and morbidity was found in this Middle Eastern PsA population, in accordance with data from other geographic regions. These results emphasize the importance of clinician awareness of the increased risk for CVD-related complications in PsA patients.

Indexed as

AdultAgedArthritis, PsoriaticCardiovascular DiseasesCase-Control StudiesCross-Sectional StudiesFemaleHumansMaleMetabolic DiseasesMiddle AgedMiddle EastMultivariate AnalysisPrevalenceRetrospective StudiesRisk FactorsCardiovascular disease (CVD) risk factorsCVD-related morbidityPsoriatic arthritis (PsA)

Identifiers

PMID30937638
OpenAlexW2926051663

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.