Evidence map›Paper›PMID 30939419›Full record

ArticleMedical image analysis2019

BIRNet: Brain image registration using dual-supervised fully convolutional networks.

Jingfan Fan, Xiaohuan Cao, Pew-Thian Yap, Dinggang Shen

Abstract readValidation Study
In one paragraph

Article in Medical image analysis, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
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  4. Review
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  6. The Fusion of Robotics and Imaging: A Vision of the Future.Methodist DeBakey cardiovascular journal · 2025
    Review
  7. Article
  8. Article
  9. Article
  10. Medical image registration and its application in retinal images: a review.Visual computing for industry, biomedicine, and art · 2024
    Review
  11. Article
  12. Unsupervised deep learning registration model for multimodal brain images.Journal of applied clinical medical physics · 2023
    Article
  13. Article
  14. Review
  15. 3D Biological/Biomedical Image Registration with enhanced Feature Extraction and Outlier Detection.ACM-BCB ... ... : the ... ACM Conference on Bioinformatics, Computational Biology and Biomedicine. ACM Conference on Bioinformatics, Computational Biology and Biomedicine · 2023
    Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article

7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jingfan FanDepartment of Radiology and BRIC, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; Beijing Engineering Research Center of Mixed Reality and Advanced Display, School of Optics and Photonics, Beijing Institute of Technology, Beijing, China.
Xiaohuan CaoShanghai United Imaging Intelligence Co. Ltd., Shanghai, China.
Pew-Thian YapDepartment of Radiology and BRIC, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Dinggang ShenDepartment of Radiology and BRIC, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; Department of Brain and Cognitive Engineering, Korea University, Seoul, Republic of Korea. Electronic address: dgshen@med.unc.edu.

Funding

Longitudinal Mapping of Human Brain Development in the First Years of LifeR01EB008374 · NIBIB · UNIV OF NORTH CAROLINA CHAPEL HILL · PI YAP, PEW-THIAN · 2009 to 2024
$5.1M
Development of Robust Brain Measurement Tools Informed by Ultrahigh Field 7T MRIR01EB006733 · NIBIB · UNIV OF NORTH CAROLINA CHAPEL HILL · PI YAP, PEW-THIAN · 2008 to 2020
$4.5M
UNC/UMN Baby Connectome ProjectU01MH110274 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ELISON, JED THOMAS, GILMORE, JOHN HORACE · 2016 to 2019
$4.5M
Quantifying Brain Abnormality by Multimodality Neuroimage Analysis,R01AG041721 · NIA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI LIU, MINGXIA · 2012 to 2019
$3.0M
Analyzing Large-Scale Neuroimaging Data in Alzheimer's DiseaseRF1AG053867 · NIA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI YAP, PEW-THIAN · 2016 to 2016
$2.5M
Infant Brain Measurement and Super-Resolution Atlas ConstructionR01MH100217 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SHEN, DINGGANG · 2013 to 2016
$2.3M
Imaging Genomics Based Brain Disease PredictionR01AG049371 · NIA · UNIVERSITY OF TEXAS ARLINGTON · PI HUANG, HENG · 2015 to 2019
$2.0M
Assessing Large-scale Brain Connectivities in Mild Cognitive ImpairmentR01AG042599 · NIA · UNIVERSITY OF GEORGIA · PI LIU, TIANMING · 2013 to 2017
$1.4M
Diagnosis of Alzheimer's Disease Using Dynamic High-Order Brain NetworksR01EB022880 · NIBIB · UNIV OF NORTH CAROLINA CHAPEL HILL · PI YAP, PEW-THIAN · 2016 to 2018
$1.1M
Constructing 4-dimensional Infant Cortical Surface AtlasesR21MH108914 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI LI, GANG · 2016 to 2017
$418k
NIA NIH HHS R01 AG041721NIA NIH HHS R01 AG042599NIA NIH HHS R01 AG049371NIA NIH HHS RF1 AG053867NIBIB NIH HHS R01 EB006733NIBIB NIH HHS R01 EB008374NIBIB NIH HHS R01 EB022880NIMH NIH HHS R01 MH100217NIMH NIH HHS R21 MH108914NIMH NIH HHS U01 MH110274
6 · The paper itself

Abstract

In this paper, we propose a deep learning approach for image registration by predicting deformation from image appearance. Since obtaining ground-truth deformation fields for training can be challenging, we design a fully convolutional network that is subject to dual-guidance: (1) Ground-truth guidance using deformation fields obtained by an existing registration method; and (2) Image dissimilarity guidance using the difference between the images after registration. The latter guidance helps avoid overly relying on the supervision from the training deformation fields, which could be inaccurate. For effective training, we further improve the deep convolutional network with gap filling, hierarchical loss, and multi-source strategies. Experiments on a variety of datasets show promising registration accuracy and efficiency compared with state-of-the-art methods.

Indexed as

Neural Networks, ComputerBrain MappingDeep LearningHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingBrain MR imageConvolutional neural networksHierarchical registrationImage registration

Identifiers

PMID30939419
PMCPMC6764428

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.