Evidence map›Paper›PMID 30946773›Full record

ArticlePloS one2019

Predicting trajectories of recovery in prostate cancer patients undergone Robot-Assisted Radical Prostatectomy (RARP).

Chiara Marzorati, Dario Monzani, Ketti Mazzocco, Francesca Pavan, Gabriele Cozzi, Ottavio De Cobelli, Massimo Monturano, Gabriella Pravettoni

Abstract read
In one paragraph

Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Chiara MarzoratiDepartment of Oncology and Hemato-Oncology, University of Milan, Milan, Italy.ORCID 0000-0001-7761-2804
Dario MonzaniDepartment of Oncology and Hemato-Oncology, University of Milan, Milan, Italy.
Ketti MazzoccoDepartment of Oncology and Hemato-Oncology, University of Milan, Milan, Italy.ORCID 0000-0003-1382-6779
Francesca PavanPatient Safety & Risk Management Service, European Institute of Oncology IRCCS, Milan, Italy.
Gabriele CozziDivision of Urology, European Institute of Oncology IRCCS, Milan, Italy.
Ottavio De CobelliDepartment of Oncology and Hemato-Oncology, University of Milan, Milan, Italy.
Massimo MonturanoPatient Safety & Risk Management Service, European Institute of Oncology IRCCS, Milan, Italy.
Gabriella PravettoniDepartment of Oncology and Hemato-Oncology, University of Milan, Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo identify trends of patients' urinary and sexual dysfunctions from a clinical and psychological perspective and understand whether sociodemographic and medical predictors could differentiate among patients following different one-year longitudinal trajectories.

methodsAn Italian sample of 478 prostate cancer patients undergone Robot-Assisted Radical Prostatectomy completed the EPIC-26 survey between July 2015 and July 2016 at the pre-hospitalization (T0), 45 days (T1) and 3 (T2), 6 (T3), 9 (T4), and 12 months (T5) after surgery. Sociodemographic and clinical characteristics (age, BMI, diabetes, nerve-sparing procedure) were also collected. Latent Class Growth Analysis was conducted separately for sexual dysfunction and urinary incontinence EPIC-26 subscales. The association between membership in the two longitudinal trajectories of urinary and sexual dysfunctions was assessed by considering Chi-square test and its related contingency table.

resultsPeople who have a high level of urinary incontinence at T1 are likely to have a worse recovery. Age, BMI and pre-surgical continence may affect the level of incontinence at T1 and the recovery trajectories. Patients with low and moderate sexual problems at T1 can face a moderate linear recovery, while people with high level of impotence immediately after surgery may take a longer period to solve sexual dysfunctions. Age and the pre-surgical sexual condition may impact the recovery. Finally, a great proportion of patients reported both steady problems in sexual function and constant high levels of urinary incontinence over time.

conclusionsThis study highlights different categories of patients at risk who may be important to know in order to develop personalized medical pathways and predictive models in a value-based healthcare.

Indexed as

Robotic Surgical ProceduresErectile DysfunctionHumansItalyMalePostoperative ComplicationsProstatectomyQuality of LifeSocioeconomic FactorsTreatment OutcomeUrinary Incontinence

Identifiers

PMID30946773
PMCPMC6448842

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.