SynthesisJournal of molecular neuroscience : MN2019
Type 2 Diabetes Mellitus Is Associated with the Risk of Cognitive Impairment: a Meta-Analysis.
Synthesis in Journal of molecular neuroscience : MN, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed.
- The relationship between sedentary time, sleep quality, glycemic control, and mild cognitive impairment in older adults with type 2 diabetes mellitus.BMC geriatrics · 2026Article
- The Role of Inflammation, Oxidative Stress, Neuronal Damage, and Endothelial Dysfunction in the Neuropathology of Cognitive Complications in Diabetes: A Moderation and Mediation Analysis.Brain and behavior · 2025Article
- The Effects of Type 2 Diabetes on Cognitive Performance: A Review of Reviews.International journal of behavioral medicine · 2024Review
- Untargeted Metabolomic Profiling Reveals Differentially Expressed Serum Metabolites and Pathways in Type 2 Diabetes Patients with and without Cognitive Decline: A Cross-Sectional Study.International journal of molecular sciences · 2024Article
- Review
- Association between Blood Glucose Control and Subjective Cognitive Decline in Korean Patients with Diabetes Aged over 50 Years.International journal of environmental research and public health · 2022Article
- Article
- Altered Regional Homogeneity in Patients With Diabetic Erectile Dysfunction: A Resting-State fMRI Study.Frontiers in endocrinology · 2022Article
- Glycemic Dysregulations Are Associated With Worsening Cognitive Function in Older Participants at High Risk of Cardiovascular Disease: Two-Year Follow-up in the PREDIMED-Plus Study.Frontiers in endocrinology · 2021Observational
- Informal Caregiving, Poor Mental Health, and Subjective Cognitive Decline: Results From a Population-Based Sample.Journal of gerontological nursing · 2020Article
- Mild Cognitive Impairment Subtypes and Type 2 Diabetes in Elderly Subjects.Journal of clinical medicine · 2020Article
- A compound reflects the level of homocysteine based on Rhodamine B and its ability to respond to homocysteine in the plasma of diabetic patients.Journal of clinical laboratory analysis · 2020Article
- Assessment of Appetite-Regulating Hormones Provides Further Evidence of Altered Adipoinsular Axis in Early Psychosis.Frontiers in psychiatry · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
The present meta-analysis aimed to evaluate the interaction between type 2 diabetes mellitus (T2DM) and the risk of cognitive impairment. The studies that fulfilled certain inclusion criteria were selected from online databases including PubMed, Embase, and the Cochrane Library. Data extraction and quality assessment were conducted, and subgroup analysis was performed according to the study area, population sources, and types of cognitive impairment. Publication bias and sensitivity analysis were evaluated. In total, 30 studies from 25 articles, including 2 case-control studies, 9 cohort studies, and 19 cross-sectional studies, were included. Subgroup analysis showed that despite the presence of hospital-based and multi-center subgroups in the cohort studies, the association between T2DM and cognitive impairment risk was statistically significant in all other subgroups (P < 0.05). Furthermore, the sensitivity and publication bias analysis showed good stability in all enrolled studies. T2DM might be associated with the risk of cognitive impairment. Further studies on early detection and appropriate management of cognitive impairment might be required in T2DM patients of different regions.
Indexed as
Identifiers
30949957What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.