Evidence map›Paper›PMID 30960878›Full record

ArticlePolymers2018

Inhibition of Tumor Growth via Systemic siRNA Delivery Using Reducible Bile Acid-Conjugated Polyethylenimine.

Yue Yin, Jung Eun Lee, Nak Won Kim, Jong Han Lee, Su Yeon Lim, E Seul Kim, Ji Won Park, Min Sang Lee, Ji Hoon Jeong

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Polymers, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Yue YinSchool of Pharmacy, Sungkyunkwan University, Suwon 16419, Korea. yinyue2013@skku.edu.
Jung Eun LeeSchool of Pharmacy, Sungkyunkwan University, Suwon 16419, Korea. jelee1213@naver.com.
Nak Won KimSchool of Pharmacy, Sungkyunkwan University, Suwon 16419, Korea. paradiseboom@naver.com.
Jong Han LeeSchool of Pharmacy, Sungkyunkwan University, Suwon 16419, Korea. chq29kr@gmail.com.
Su Yeon LimSchool of Pharmacy, Sungkyunkwan University, Suwon 16419, Korea. suuyeon37@skku.edu.
E Seul KimSchool of Pharmacy, Sungkyunkwan University, Suwon 16419, Korea. seul4146@naver.com.
Ji Won ParkSchool of Pharmacy, Sungkyunkwan University, Suwon 16419, Korea. jwjwpar@gmail.com.
Min Sang LeeSchool of Pharmacy, Sungkyunkwan University, Suwon 16419, Korea. lminsa@skku.edu.
Ji Hoon JeongSchool of Pharmacy, Sungkyunkwan University, Suwon 16419, Korea. jhjeong@skku.edu.ORCID 0000-0002-4836-3551
Sungkyunkwan University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

RNA interference (RNAi), mediated by small interfering RNA (siRNA), has been considered as a potential therapeutic agent for cancer owing to its ability to suppress target genes in a sequence-specific manner. In this study, a conjugate of the low molecular weight (M

Indexed as

deoxycholic aciddisulfide crosslinkingsmall interfering RNAstabilized polyplexsystemic gene therapy

Identifiers

PMID30960878
PMCPMC6403700
OpenAlexW2889401554

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.