Evidence map›Paper›PMID 30966882›Full record

ArticlePhilosophical transactions of the Royal Society of London. Series B, Biological sciences2019

Developing differences: early-life effects and evolutionary medicine.

Bram Kuijper, Mark A Hanson, Emma I K Vitikainen, Harry H Marshall, Susan E Ozanne, Michael A Cant

Abstract read
In one paragraph

Article in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Delayed early life effects in the threespine stickleback.Proceedings. Biological sciences · 2022
    Article
  6. Article
  7. The evolution of social learning as phenotypic cue integration.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021
    Article
  8. Article
  9. Stress and Learning in Pupils: Neuroscience Evidence and its Relevance for Teachers.Mind, brain and education : the official journal of the International Mind, Brain, and Education Society · 2021
    Review
  10. International journal of molecular sciences · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Bram Kuijper1 Environment and Sustainability Institute , Penryn Campus, University of Exeter, Penryn TR10 IEZ , UK.
Mark A Hanson3 Institute of Developmental Sciences and NIHR Southampton Biomedical Research Centre, Southampton University Hospital and University of Southampton , UK.
Emma I K Vitikainen2 Centre for Ecology and Conservation , Penryn Campus, University of Exeter, Penryn TR10 IEZ , UK.
Harry H Marshall2 Centre for Ecology and Conservation , Penryn Campus, University of Exeter, Penryn TR10 IEZ , UK.
Susan E Ozanne6 University of Cambridge - Department of Clinical Biochemistry , Hills Road, Addenbrookes Level 4, Box 232 Cambridge CB2 2QR , UK.
Michael A Cant2 Centre for Ecology and Conservation , Penryn Campus, University of Exeter, Penryn TR10 IEZ , UK.

Funding

British Heart Foundation RG/15/17/31749Medical Research Council MC_UU_00014/4Medical Research Council MC_UU_12012/4Medical Research Council MC_UU_12012/5
6 · The paper itself

Abstract

Variation in early-life conditions can trigger developmental switches that lead to predictable individual differences in adult behaviour and physiology. Despite evidence for such early-life effects being widespread both in humans and throughout the animal kingdom, the evolutionary causes and consequences of this developmental plasticity remain unclear. The current issue aims to bring together studies of early-life effects from the fields of both evolutionary ecology and biomedicine to synthesise and advance current knowledge of how information is used during development, the mechanisms involved, and how early-life effects evolved. We hope this will stimulate further research into early-life effects, improving our understanding of why individuals differ and how this might influence their susceptibility to disease. This article is part of the theme issue 'Developing differences: early-life effects and evolutionary medicine'.

Indexed as

Adaptation, PhysiologicalBiological EvolutionLife History TraitsMedicinePhenotypeAnimalsGrowth and DevelopmentHuman DevelopmentHumansdevelopmental plasticityepigeneticsgrowthnutritionparental effectpredictive adaptive response

Identifiers

PMID30966882
PMCPMC6460072

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.