Evidence map›Paper›PMID 30967004›Full record

ArticlePhilosophical transactions of the Royal Society of London. Series B, Biological sciences2019

Macropinocytosis and autophagy crosstalk in nutrient scavenging.

Oliver Florey, Michael Overholtzer

Abstract read
In one paragraph

Article in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Article
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  9. Article
  10. Autophagy and tumorigenesis.The FEBS journal · 2022
    Review
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  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Oliver Florey1 Signalling Programme, Babraham Institute , Cambridge CB22 3AT , UK.
Michael Overholtzer2 Cell Biology Program, Memorial Sloan Kettering Cancer Center , New York, NY 10065 , USA.

Funding

The role of entosis in human cancersR01CA154649 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI OVERHOLTZER, MICHAEL H. · 2011 to 2020
$3.9M
Biotechnology and Biological Sciences Research Council BBS/E/B/000C0413Cancer Research UK 16337Cancer Research UK C47718/A16337NCI NIH HHS R01 CA154649
6 · The paper itself

Abstract

Adaptive strategies used by cells to scavenge and recycle essential nutrients are important for survival in nutrient-depleted environments such as cancer tissues. Autophagy and macropinocytosis are two major mechanisms that promote nutrient recycling and scavenging, which share considerable, yet poorly understood, cross-regulation. Here we review recent findings that connect these starvation response mechanisms and discuss the implications of their crosstalk. This article is part of the Theo Murphy meeting issue 'Macropinocytosis'.

Indexed as

AnimalsAutophagyHumansNutrientsPinocytosisNutrientsautophagyentosis, phagocytosismacropinocytosis

Identifiers

PMID30967004
PMCPMC6304738

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.