ReviewDigestive diseases and sciences2019
Obesity and the Risk of Gastrointestinal Cancers.
Review in Digestive diseases and sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 64 citations in OpenAlex.
- Sex and Gender Perspective in Obesity and Gastric Cancer.The world journal of men's health · 2026Review
- The association of diet-dependent acid load with gastrointestinal cancer risk in the Cancer Screenee Cohort in Korea.European journal of clinical nutrition · 2025Article
- The Oncogenic Burden of Obesity: Mechanistic Links Between Adiposity and Gastrointestinal Cancers-A Comprehensive Narrative Review.Biomedicines · 2025Review
- Common Risk Factors in Gastrointestinal Cancers: A Narrative Review.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2025Review
- Conjugated Linoleic Acid in Cancer Therapy.Current drug delivery · 2025Review
- Nurse night shift work and risk of gastrointestinal cancers.Frontiers in public health · 2025Review
- Liraglutide alleviates high-fat diet-induced kidney injury in mice by regulating the CaMKKβ/AMPK pathway.Renal failure · 2024Article
- Review
- The signaling pathways in obesity-related complications.Journal of cell communication and signaling · 2024Review
- Very low-calorie ketogenic diet (VLCKD): a therapeutic nutritional tool for acne?Journal of translational medicine · 2024Article
- Methanol extract ofJournal of animal science and technology · 2024Article
- Body fat ratio as a novel predictor of complications and survival after rectal cancer surgery.Frontiers in nutrition · 2024Article
- Assessment of the Role of Leptin and Adiponectinas Biomarkers in Pancreatic Neuroendocrine Neoplasms.Cancers · 2023Article
- Prognostic significance of controlling nutritional status score for patients with gastric cancer: A systematic review and meta‑analysis.Experimental and therapeutic medicine · 2023Article
- Article
- The utility of endoscopy prior to bariatric surgery: an 11-year retrospective analysis of 885 patients.Surgical endoscopy · 2023Article
- Systemic Diseases and Gastrointestinal Cancer Risk.Journal of cancer & allied specialties · 2023Review
- Obesity promotes lipid accumulation in lymph node metastasis of gastric cancer: a retrospective case‒control study.Lipids in health and disease · 2022Article
- Advances and development of prostate cancer, treatment, and strategies: A systemic review.Frontiers in cell and developmental biology · 2022Review
- microRNA-377-3p downregulates the oncosuppressor T-cadherin in colorectal adenocarcinoma cells.Cell biology international · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Obesity is a risk factor for all major gastrointestinal cancers. With the rapid increase in the prevalence of obesity worldwide, this link could lead to an elevated burden of cancers of the digestive system. Currently, three main mechanisms explaining the link between excess adiposity and gastrointestinal cancer risk are being considered, including altered insulin signaling, obesity-associated chronic low-grade inflammation, and altered sex hormone metabolism, although new potential mechanisms emerge. This review is aimed to present our current knowledge on biological mechanisms involved in adiposity-related gastrointestinal carcinogenesis supported by results collected in epidemiological studies.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.