Evidence map›Paper›PMID 30976157›Full record

ReviewJournal of ginseng research2019

Emerging signals modulating potential of ginseng and its active compounds focusing on neurodegenerative diseases.

Md Jakaria, Joonsoo Kim, Govindarajan Karthivashan, Shin-Young Park, Palanivel Ganesan, Dong-Kug Choi

Open access · goldAbstract readReview
In one paragraph

Review in Journal of ginseng research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 29 citations in OpenAlex.

  1. Review
  2. Article
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  9. Review
  10. Article
  11. Review
  12. The Methanol Extract ofAntioxidants (Basel, Switzerland) · 2019
    Article
  13. Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Md JakariaDepartment of Applied Life Science, Graduate School, Konkuk University, Chungju, Republic of Korea.
Joonsoo KimDepartment of Applied Life Science, Graduate School, Konkuk University, Chungju, Republic of Korea.
Govindarajan KarthivashanResearch Institute of Inflammatory Disease, and Department of Biotechnology, College of Biomedical and Health Science, Konkuk University, Chungju 27478, Korea.
Shin-Young ParkDepartment of Applied Life Science, Graduate School, Konkuk University, Chungju, Republic of Korea.
Palanivel GanesanResearch Institute of Inflammatory Disease, and Department of Biotechnology, College of Biomedical and Health Science, Konkuk University, Chungju 27478, Korea.
Dong-Kug ChoiDepartment of Applied Life Science, Graduate School, Konkuk University, Chungju, Republic of Korea.
Konkuk University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Common features of neurodegenerative diseases (NDDs) include progressive dysfunctions and neuronal injuries leading to deterioration in normal brain functions. At present, ginseng is one of the most frequently used natural products. Its use has a long history as a cure for various diseases because its extracts and active compounds exhibit several pharmacological properties against several disorders. However, the pathophysiology of NDDs is not fully clear, but researchers have found that various ion channels and specific signaling pathways might have contributed to the disease pathogenesis. Apart from the different pharmacological potentials, ginseng and its active compounds modulate various ion channels and specific molecular signaling pathways related to the nervous system. Here, we discuss the signal modulating potential of ginseng and its active compounds mainly focusing on those relevant to NDDs.

Indexed as

Active compoundsGinsengIon channelsNeurodegenerative diseasesSignaling pathway

Identifiers

PMID30976157
PMCPMC6437449
OpenAlexW2791866597

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.