ReviewMedical microbiology and immunology2019
Impact of cytomegalovirus load on host response to sepsis.
Review in Medical microbiology and immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed.
- Detection of cytomegalovirus in the lower respiratory tract among patients with critical illness: uncovering enhanced potential benefits.Critical care (London, England) · 2025Article
- Active cytomegalovirus infection in mechanically ventilated patients with sepsis.BMC infectious diseases · 2024Article
- Increased Levels of Anti-Antibodies (Basel, Switzerland) · 2024Article
- Drugs Targeting Sirtuin 2 Exhibit Broad-Spectrum Anti-Infective Activity.Pharmaceuticals (Basel, Switzerland) · 2024Review
- Cytomegalovirus end-organ disease in immunocompromised critically ill patients: key concerns demanding attention.Critical care (London, England) · 2024Article
- Effect of Cytomegalovirus Infection on the Central Nervous System: Implications for Psychiatric Disorders.Current topics in behavioral neurosciences · 2023Article
- Reactivation of latent human cytomegaloviral infection in critically ill patients.The Indian journal of medical research · 2022Article
- Cytomegalovirus reactivation in immunocompetent mechanical ventilation patients: a prospective observational study.BMC infectious diseases · 2021Observational
- Respiratory viral sepsis: epidemiology, pathophysiology, diagnosis and treatment.European respiratory review : an official journal of the European Respiratory Society · 2020Review
- Pediatric roots of cytomegalovirus recurrence and memory inflation in the elderly.Medical microbiology and immunology · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There is a decades old association between cytomegalovirus reactivation and sepsis in immune-competent hosts. Much has been learned about this relationship, which has been described as bidirectional, meaning that the virus incites and is incited by the host's inflammatory response. More recent work has suggested that chronic viral infection leaves the host with exaggerated immunity to bacterial infections. In this review, the relationship between CMV and host responses to sepsis are reviewed, with particular attention to the impact that tissue viral load contributes to this phenomenon.
Indexed as
Identifiers
30976913What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.