Evidence map›Paper›PMID 30984338›Full record

ArticleOxidative medicine and cellular longevity2019

Hydrogen and Oxygen Mixture to Improve Cardiac Dysfunction and Myocardial Pathological Changes Induced by Intermittent Hypoxia in Rats.

Ya-Shuo Zhao, Ji-Ren An, Shengchang Yang, Peng Guan, Fu-Yang Yu, Wenya Li, Jie-Ru Li, Yajing Guo, Zhi-Min Sun, En-Sheng Ji

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
8.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 61 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. The Protective Role of Molecular Hydrogen in Ischemia/Reperfusion Injury.International journal of molecular sciences · 2024
    Review
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  7. Article
  8. Review
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  11. Article
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  13. Article
  14. Article
  15. Review
  16. Obstructive Sleep Apnea Affects Lacrimal Gland Function.Investigative ophthalmology & visual science · 2022
    Article
  17. Hydrogen: A Novel Treatment Strategy in Kidney Disease.Kidney diseases (Basel, Switzerland) · 2022
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Ya-Shuo ZhaoScientific Research Center, Hebei University of Chinese Medicine, Shijiazhuang 050200, China.ORCID 0000-0002-5793-5574
Ji-Ren AnDepartment of Physiology, Institute of Basic Medicine, Hebei University of Chinese Medicine, Shijiazhuang 050200, China.ORCID 0000-0001-5274-8289
Shengchang YangDepartment of Physiology, Institute of Basic Medicine, Hebei University of Chinese Medicine, Shijiazhuang 050200, China.ORCID 0000-0002-2002-4945
Peng GuanDepartment of Physiology, Institute of Basic Medicine, Hebei University of Chinese Medicine, Shijiazhuang 050200, China.ORCID 0000-0002-1535-6216
Fu-Yang YuDepartment of Physiology, Institute of Basic Medicine, Hebei University of Chinese Medicine, Shijiazhuang 050200, China.ORCID 0000-0002-9992-5972
Wenya LiDepartment of Physiology, Institute of Basic Medicine, Hebei University of Chinese Medicine, Shijiazhuang 050200, China.ORCID 0000-0002-0681-385X
Jie-Ru LiDepartment of Physiology, Institute of Basic Medicine, Hebei University of Chinese Medicine, Shijiazhuang 050200, China.ORCID 0000-0001-6932-647X
Yajing GuoScientific Research Center, Hebei University of Chinese Medicine, Shijiazhuang 050200, China.ORCID 0000-0001-6336-0415
Zhi-Min SunDepartment of Physiology, Institute of Basic Medicine, Hebei University of Chinese Medicine, Shijiazhuang 050200, China.ORCID 0000-0001-6020-0627
En-Sheng JiDepartment of Physiology, Institute of Basic Medicine, Hebei University of Chinese Medicine, Shijiazhuang 050200, China.ORCID 0000-0002-5858-7567
Hebei University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Obstructive sleep apnea (OSA) can cause intermittent changes in blood oxygen saturation, resulting in the generation of many reactive oxygen species (ROS). To discover new antioxidants and clarify the endoplasmic reticulum (ER) stress involved in cardiac injury in OSA, we established a chronic intermittent hypoxia (CIH) rat model with a fraction of inspired O

Indexed as

AnimalsApoptosisCell HypoxiaDisease Models, AnimalHeart DiseasesHumansHydrogenMaleMyocardiumOxygenRatsRats, Sprague-DawleyReactive Oxygen SpeciesSleep Apnea, ObstructiveHydrogenOxygenReactive Oxygen Species

Identifiers

PMID30984338
PMCPMC6431505
OpenAlexW2921207990

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.