Evidence map›Paper›PMID 30987300›Full record

ArticleToxins2019

Understanding the Significance of Biochemistry in the Storage, Handling, Purification, and Sampling of Amphiphilic Mycolactone.

Jessica Z Kubicek-Sutherland, Dung M Vu, Aaron S Anderson, Timothy C Sanchez, Paul J Converse, Ricardo Martí-Arbona, Eric L Nuermberger, Basil I Swanson, Harshini Mukundan

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Toxins, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Conditions for Handling and Optimal Storage of Mycolactone.Methods in molecular biology (Clifton, N.J.) · 2022
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. The Many Hosts of Mycobacteria 8 (MHM8): A conference report.Tuberculosis (Edinburgh, Scotland) · 2020
    Review
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Jessica Z Kubicek-SutherlandChemistry Division, Los Alamos National Laboratory, Los Alamos, NM 87545, USA. jzk@lanl.gov.ORCID 0000-0001-6215-4871
Dung M VuChemistry Division, Los Alamos National Laboratory, Los Alamos, NM 87545, USA. dvu@lanl.gov.
Aaron S AndersonChemistry Division, Los Alamos National Laboratory, Los Alamos, NM 87545, USA. aaronsa@lanl.gov.
Timothy C SanchezBioscience Division, Los Alamos National Laboratory, Los Alamos, NM 87545, USA. tim_san@lanl.gov.
Paul J ConverseDepartment of Medicine, Johns Hopkins University Center for Tuberculosis Research, Baltimore, MD 21218, USA. pconver1@jhmi.edu.
Ricardo Martí-ArbonaBioscience Division, Los Alamos National Laboratory, Los Alamos, NM 87545, USA. rm-a@lanl.gov.ORCID 0000-0002-9720-977X
Eric L NuermbergerDepartment of Medicine, Johns Hopkins University Center for Tuberculosis Research, Baltimore, MD 21218, USA. enuermb@jhmi.edu.
Basil I SwansonBioscience Division, Los Alamos National Laboratory, Los Alamos, NM 87545, USA. basil@lanl.gov.
Harshini MukundanChemistry Division, Los Alamos National Laboratory, Los Alamos, NM 87545, USA. harshini@lanl.gov.
Los Alamos National Laboratory · USJohns Hopkins University · US

Funding

Closing the Gaps on Buruli Ulcer Diagnosis, Treatment, and PreventionR01AI113266 · NIAID · JOHNS HOPKINS UNIVERSITY · PI NUERMBERGER, ERIC L · 2016 to 2020
$4.4M
National Institute of Allergy and Infectious Diseases R01AI113266NIAID NIH HHS R01 AI113266
6 · The paper itself

Abstract

Mycolactone, the amphiphilic macrolide toxin secreted by

Indexed as

Bacterial ToxinsMacrolidesAnimalsCell LineCell SurvivalChromatography, Thin LayerHumansLipoproteins, HDLLipoproteins, LDLMiceMycobacterium ulceransSpectrometry, Mass, Electrospray IonizationSpectrophotometry, UltravioletBacterial ToxinsLipoproteins, HDLLipoproteins, LDLMacrolidesmycolactoneamphiphiliclipoproteinsmycolactonestorage and handling

Identifiers

PMID30987300
PMCPMC6520765
OpenAlexW2927893242

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.