Evidence map›Paper›PMID 30988342›Full record

ArticleScientific reports2019

Detection of T lymphocyte subsets and related functional molecules in follicular fluid of patients with polycystic ovary syndrome.

Zitao Li, Anping Peng, Yuanfa Feng, Xiaona Zhang, Fenghua Liu, Chuangqi Chen, Xin Ye, Jiale Qu, Chenxi Jin, Mei Wang and 4 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
3.0field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 40 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Zitao LiReproductive medical center, Guangdong Women and Children Hospital, Guangzhou Medical University, 511400, Guangzhou, China.
Anping PengClinical laboratory, Traditional Chinese Medicine Hospital of Guangdong province, 510120, Guangzhou, China.
Yuanfa FengDepartment of Pathogenic Biology and Immunology, Sino-French Hoffmann Institute, Guangzhou Medical University, 511436, Guangzhou, China.
Xiaona ZhangThe Sixth Affiliated Hospital of Sun Yat-Sen University, 510655, Guangzhou, China.
Fenghua LiuReproductive medical center, Guangdong Women and Children Hospital, Guangzhou Medical University, 511400, Guangzhou, China.
Chuangqi ChenReproductive medical center, Guangdong Women and Children Hospital, Guangzhou Medical University, 511400, Guangzhou, China.
Xin YeDepartment of Pathogenic Biology and Immunology, Sino-French Hoffmann Institute, Guangzhou Medical University, 511436, Guangzhou, China.
Jiale QuDepartment of Pathogenic Biology and Immunology, Sino-French Hoffmann Institute, Guangzhou Medical University, 511436, Guangzhou, China.
Chenxi JinDepartment of Pathogenic Biology and Immunology, Sino-French Hoffmann Institute, Guangzhou Medical University, 511436, Guangzhou, China.
Mei WangDepartment of Pathogenic Biology and Immunology, Sino-French Hoffmann Institute, Guangzhou Medical University, 511436, Guangzhou, China.
Huaina QiuDepartment of Pathogenic Biology and Immunology, Sino-French Hoffmann Institute, Guangzhou Medical University, 511436, Guangzhou, China.
Yanwei QiDepartment of Pathogenic Biology and Immunology, Sino-French Hoffmann Institute, Guangzhou Medical University, 511436, Guangzhou, China.
Jun HuangDepartment of Pathogenic Biology and Immunology, Sino-French Hoffmann Institute, Guangzhou Medical University, 511436, Guangzhou, China. hj165@sina.com.ORCID http://orcid.org/0000-0002-6135-1256
Quan YangReproductive medical center, Guangdong Women and Children Hospital, Guangzhou Medical University, 511400, Guangzhou, China. yquangy2015@gzhmu.edu.cn.
Guangzhou Medical University · CNFirst Affiliated Hospital of Guangzhou Medical University · CNGuangdong Provincial Hospital of Traditional Chinese Medicine · CNSun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immune responses play an important role in the pathogenesis of polycystic ovary syndrome (PCOS). However, the characteristics of T lymphocyte subsets in PCOS remain insufficiently understood. In this study, lymphocytes of follicular fluid (FF) were obtained from oocyte retrieval before in-vitro fertilization (IVF) in infertile women with or without PCOS. The levels of cluster of differentiation 25 (CD25), CD69, programmed death 1 (PD-1), interferon-γ (IFN-γ), interleukin 17A (IL-17A) and IL-10 in T lymphocytes were determined by flow cytometry. Our results showed that the percentage of FF CD8

Indexed as

AdultAntigens, CDAntigens, Differentiation, T-LymphocyteCD4-Positive T-LymphocytesCD69 AntigensCD8-Positive T-LymphocytesCytokinesFemaleFertilization in VitroFollicular FluidHumansInfertility, FemaleInterleukin-2 Receptor alpha SubunitLectins, C-TypePolycystic Ovary SyndromeT-Lymphocyte SubsetsAntigens, CDAntigens, Differentiation, T-LymphocyteCD69 AntigensCytokinesIL2RA protein, humanInterleukin-2 Receptor alpha SubunitLectins, C-Type

Identifiers

PMID30988342
PMCPMC6465402
OpenAlexW2940413781

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.