ArticleCellular and molecular life sciences : CMLS2019
Bcl-2 and IP
Open access · greenAbstract read
In one paragraph
Article in Cellular and molecular life sciences : CMLS, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 41 citations in OpenAlex.
- Effects of different dietary methionine and cysteine ratios on growth performance and intestinal development of broilers from brain-gut peptide secretion perspective.Animal bioscience · 2026Article
- CISD2 ensures adequate ER-mitochondrial coupling, critically supporting mitochondrial function in neurons.Acta neuropathologica communications · 2025Article
- The BCL2 family: from apoptosis mechanisms to new advances in targeted therapy.Signal transduction and targeted therapy · 2025Review
- The endoplasmic reticulum pool of Bcl-xL prevents cell death through IP3R-dependent calcium release.Cell death discovery · 2024Article
- Bcl-xL acts as an inhibitor of IPCell death and differentiation · 2022Article
- iRhom pseudoproteases regulate ER stress-induced cell death through IPNature communications · 2022Article
- Mitochondria-Endoplasmic Reticulum Contacts: The Promising Regulators in Diabetic Cardiomyopathy.Oxidative medicine and cellular longevity · 2022Review
- Stomata at the crossroad of molecular interaction between biotic and abiotic stress responses in plants.Frontiers in plant science · 2022Review
- Allosteric cross-talk between the hydrophobic cleft and the BH4 domain of Bcl-2 in control of inositol 1,4,5-trisphosphate receptor activity.Exploration of targeted anti-tumor therapy · 2022Article
- The role of Bcl-2 proteins in modulating neuronal CaBiochimica et biophysica acta. Molecular cell research · 2021Review
- Regulation of Cell Death by Mitochondrial Transport Systems of Calcium and Bcl-2 Proteins.Membranes · 2020Review
- DLBCL Cells with Acquired Resistance to Venetoclax Are Not Sensitized to BIRD-2 But Can Be Resensitized to Venetoclax through Bcl-XL Inhibition.Biomolecules · 2020Article
- Lessons from the Endoplasmic Reticulum CaCells · 2020Review
- Bcl-2-Protein Family as Modulators of IPCold Spring Harbor perspectives in biology · 2020Review
- Mitochondria-Associated Endoplasmic Reticulum Membranes in the Pathogenesis of Type 2 Diabetes Mellitus.Frontiers in cell and developmental biology · 2020Review
- Partners in Crime: Towards New Ways of Targeting Calcium Channels.International journal of molecular sciences · 2019Review
- Piezo1 induced apoptosis of type II pneumocytes during ARDS.Respiratory research · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors at 6 institutions in 4 countries.
Hristina IvanovaLaboratory of Molecular and Cellular Signaling, Department of Cellular and Molecular Medicine, Leuven Cancer Institute (LKI), KU Leuven, Campus Gasthuisberg O/N-1 Bus 802, Herestraat 49, 3000, Leuven, Belgium.
Larry E WagnerUniversity of Rochester Medical Center School of Medicine and Dentistry, 601 Elmwood Ave, Box 711, Rochester, NY, 14642, USA.
Akihiko TanimuraDepartment of Pharmacology, School of Dentistry, Health Sciences University of Hokkaido, Kita-121757 Kanazawa, Ishikari-Tobetsu, Hokkaido, 061-0293, Japan.
Elien VandermarliereCenter for Medical Biotechnology, VIB-UGent, 9000, Ghent, Belgium.
Tomas LuytenLaboratory of Molecular and Cellular Signaling, Department of Cellular and Molecular Medicine, Leuven Cancer Institute (LKI), KU Leuven, Campus Gasthuisberg O/N-1 Bus 802, Herestraat 49, 3000, Leuven, Belgium.
Kirsten WelkenhuyzenLaboratory of Molecular and Cellular Signaling, Department of Cellular and Molecular Medicine, Leuven Cancer Institute (LKI), KU Leuven, Campus Gasthuisberg O/N-1 Bus 802, Herestraat 49, 3000, Leuven, Belgium.
Kamil J AlzayadyUniversity of Rochester Medical Center School of Medicine and Dentistry, 601 Elmwood Ave, Box 711, Rochester, NY, 14642, USA.
Liwei WangUniversity of Rochester Medical Center School of Medicine and Dentistry, 601 Elmwood Ave, Box 711, Rochester, NY, 14642, USA.
Kozo HamadaLab Developmental Neurobiology, RIKEN Brain Science Institute, 2-1 Hirosawa Wako-Shi, 351-0198, Saitama, Japan.
Katsuhiko MikoshibaLab Developmental Neurobiology, RIKEN Brain Science Institute, 2-1 Hirosawa Wako-Shi, 351-0198, Saitama, Japan.
Humbert De SmedtLaboratory of Molecular and Cellular Signaling, Department of Cellular and Molecular Medicine, Leuven Cancer Institute (LKI), KU Leuven, Campus Gasthuisberg O/N-1 Bus 802, Herestraat 49, 3000, Leuven, Belgium.
Lennart MartensCenter for Medical Biotechnology, VIB-UGent, 9000, Ghent, Belgium.ORCID http://orcid.org/0000-0003-4277-658X
David I YuleUniversity of Rochester Medical Center School of Medicine and Dentistry, 601 Elmwood Ave, Box 711, Rochester, NY, 14642, USA.ORCID http://orcid.org/0000-0002-6743-0668
Jan B ParysLaboratory of Molecular and Cellular Signaling, Department of Cellular and Molecular Medicine, Leuven Cancer Institute (LKI), KU Leuven, Campus Gasthuisberg O/N-1 Bus 802, Herestraat 49, 3000, Leuven, Belgium.ORCID http://orcid.org/0000-0002-3591-4967
Geert BultynckLaboratory of Molecular and Cellular Signaling, Department of Cellular and Molecular Medicine, Leuven Cancer Institute (LKI), KU Leuven, Campus Gasthuisberg O/N-1 Bus 802, Herestraat 49, 3000, Leuven, Belgium. geert.bultynck@kuleuven.be.ORCID http://orcid.org/0000-0002-5968-4828
KU Leuven · BEUniversity of Rochester Medical Center · USRIKEN Center for Brain Science · JPUniversity College Ghent · BEHealth Sciences University of Hokkaido · JPVIB-KU Leuven Center for Cancer Biology · BE
Funding
Fonds Wetenschappelijk Onderzoek 6.057.12Fonds Wetenschappelijk Onderzoek G.0819.13Fonds Wetenschappelijk Onderzoek G.0901.18Fonds Wetenschappelijk Onderzoek G.0A34.16Fonds Wetenschappelijk Onderzoek G.0C91.14Onderzoeksraad, KU Leuven OT grant 14/101Vlaamse Interuniversitaire Raad IAP-P7/13
Abstract
Bcl-2 proteins have emerged as critical regulators of intracellular Ca
Indexed as
Calcium SignalingAdenosineAmino Acid SequenceAnimalsBinding, CompetitiveCells, CulturedChlorocebus aethiopsCOS CellsInositol 1,4,5-TrisphosphateInositol 1,4,5-Trisphosphate ReceptorsLigandsMiceMolecular Docking SimulationProtein DomainsProto-Oncogene Proteins c-bcl-2Sequence Deletionadenophostin AAdenosineInositol 1,4,5-TrisphosphateInositol 1,4,5-Trisphosphate ReceptorsLigandsProto-Oncogene Proteins c-bcl-2Calcium channelsInhibitionInositol 1,4,5-trisphosphate receptorLigand-binding domainLigand–receptor interactionMechanism of interactionProtein binding
Identifiers
What Socratic holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.