Evidence map›Paper›PMID 30991867›Full record

ArticleInterventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences2019

Medium-term results of undersized angioplasty and stenting for symptomatic high-grade intracranial atherosclerotic stenosis with Enterprise.

Aysun Erbahceci Salik, Hatem H Selcuk, Hasanagha Zalov, Fatih Kilinc, Musa Cirak, Batuhan Kara

Registry-linked trialAbstract read
In one paragraph

Article in Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05316311 (Implantation of CERENOVUS ENTERPRISE 2 Intracranial Stent in Patients With Severe Symptomatic Intracranial Atherosclerotic Stenosis), which is not on this map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05316311 nacompletednot on this mapstarted 2022, after this paper: background citation

Implantation of CERENOVUS ENTERPRISE 2 Intracranial Stent in Patients With Severe Symptomatic Intracranial Atherosclerotic Stenosis: A Multicenter, Prospective and Single-Arm Study in China

TypeinterventionalSponsorMedos International SARLRan2022 to 2025Enrolled194ConditionsIntracranial AtherosclerosisArmsCERENOVUS ENTERPRISE 2 Intracranial Stent
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Optional or optimal? off-label stenting for intracranial atherosclerotic stenosis: A scoping review.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
    Article
  4. Short-term outcome of stenting with Enterprise stents for symptomatic intracranial atherosclerotic disease at a single center.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2023
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Aysun Erbahceci SalikDepartment of Radiology, University of Health Sciences, Dr Sadi Konuk Training and Research Hospital, Istanbul, Turkey.ORCID https://orcid.org/0000-0001-5344-560X
Hatem H SelcukDepartment of Radiology, University of Health Sciences, Dr Sadi Konuk Training and Research Hospital, Istanbul, Turkey.
Hasanagha ZalovDepartment of Radiology, University of Health Sciences, Dr Sadi Konuk Training and Research Hospital, Istanbul, Turkey.
Fatih KilincDepartment of Radiology, University of Health Sciences, Dr Sadi Konuk Training and Research Hospital, Istanbul, Turkey.
Musa CirakDepartment of Neurosurgery, Dr Sadi Konuk Training and Research Hospital, Istanbul, Turkey.ORCID https://orcid.org/0000-0002-0175-9655
Batuhan KaraDepartment of Radiology, University of Health Sciences, Dr Sadi Konuk Training and Research Hospital, Istanbul, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of this retrospective study is to evaluate medium-term results of undersized balloon angioplasty and stenting for symptomatic high-grade (70-99%) stenosis of a major intracranial artery with Enterprise stent.

methodsThis study included 68 consecutive symptomatic (recurrent transient ischemic attack (TIA) or ischemic stroke under dual antiplatelet treatment) patients with high-grade (70-99%) stenosis of a major intracranial artery who were endovascularly treated with undersized balloon angioplasty and Enterprise stent deployment between July 2012 and December 2017. Primary outcomes were any stroke or death within 30 days after procedure. Secondary outcomes were technical success rates, stroke and restenosis during the follow-up period.

resultsA total of 68 lesions in 68 patients (mean age: 62 ± 7 years) were treated with a technical success rate of 99%. The degree of pre-procedural stenosis was 92 ± 6% and dropped to 12 ± 10% after stent deployment. No patient developed any stroke or death during the periprocedural period. Intracranial hemorrhage was observed in 1 (1.5%) patient. In 60 (88%) patients with available imaging follow-up in-stent restenosis was observed in 2 patients. Mean follow-up period was 22 ± 17 months (range 6-72) and none of the patients experienced recurrent TIA or stroke during the follow-up period.

conclusionIn this retrospective single-center study undersized balloon angioplasty and deployment of a self-expandable stent with relatively low radial force was safe and effective for endovascular treatment of high-grade intracranial arterial stenosis with high technical success rate, low periprocedural complication rates and favorable medium-term follow-up results.

Indexed as

StentsAgedAged, 80 and overAngiography, Digital SubtractionAngioplastyComputed Tomography AngiographyConstriction, PathologicEndovascular ProceduresFemaleFollow-Up StudiesGraft Occlusion, VascularHumansIntracranial ArteriosclerosisIntracranial HemorrhagesIschemic Attack, TransientMaleEnterpriseintracranial high-grade stenosisstentingtransluminal angioplasty

Identifiers

PMID30991867
PMCPMC6777118

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.