Evidence map›Paper›PMID 31000773›Full record

ArticleScientific reports2019

Application of tabu search-based Bayesian networks in exploring related factors of liver cirrhosis complicated with hepatic encephalopathy and disease identification.

Zhuang Zhang, Jie Zhang, Zhen Wei, Hao Ren, Weimei Song, Jinhua Pan, Jinchun Liu, Yanbo Zhang, Lixia Qiu

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Zhuang ZhangDepartment of Health Statistics, School of Public Health, Shanxi Medical University, No.56 XinJian South Road, Taiyuan, Shanxi, 030001, China.
Jie ZhangDepartment of Basis, Jinci College of Shanxi Medical University, No.2 Jinliao Road, Jinci Town, Jinyuan District, Taiyuan, Shanxi, 030025, China.
Zhen WeiPuruisheng (Beijing) Pharmaceutical Technology Development Co., Ltd., No. 188 South Fourth Ring Road, Fengtai District, Beijing, 100071, China.
Hao RenDepartment of Health Statistics, School of Public Health, Shanxi Medical University, No.56 XinJian South Road, Taiyuan, Shanxi, 030001, China.
Weimei SongDepartment of Health Statistics, School of Public Health, Shanxi Medical University, No.56 XinJian South Road, Taiyuan, Shanxi, 030001, China.
Jinhua PanDepartment of Health Statistics, School of Public Health, Shanxi Medical University, No.56 XinJian South Road, Taiyuan, Shanxi, 030001, China.
Jinchun LiuDepartment of Gastroenterology, First Hospital of Shanxi Medical University, No.85 JieFang South Road, Taiyuan, Shanxi, 030001, China.
Yanbo ZhangDepartment of Health Statistics, School of Public Health, Shanxi Medical University, No.56 XinJian South Road, Taiyuan, Shanxi, 030001, China.
Lixia QiuDepartment of Health Statistics, School of Public Health, Shanxi Medical University, No.56 XinJian South Road, Taiyuan, Shanxi, 030001, China. qlx_1126@163.com.
Shanxi Medical University · CNBeijing Fengtai Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to explore the related factors and strengths of hepatic cirrhosis complicated with hepatic encephalopathy (HE) by multivariate logistic regression analysis and tabu search-based Bayesian networks (BNs), and to deduce the probability of HE in patients with cirrhosis under different conditions through BN reasoning. Multivariate logistic regression analysis indicated that electrolyte disorders, infections, poor spirits, hepatorenal syndrome, hepatic diabetes, prothrombin time, and total bilirubin are associated with HE. Inferences by BNs found that infection, electrolyte disorder and hepatorenal syndrome are closely related to HE. Those three variables are also related to each other, indicating that the occurrence of any of those three complications may induce the other two complications. When those three complications occur simultaneously, the probability of HE may reach 0.90 or more. The BN constructed by the tabu search algorithm can analyze not only how the correlative factors affect HE but also their interrelationships. Reasoning using BNs can describe how HE is induced on the basis of the order in which doctors acquire patient information, which is consistent with the sequential process of clinical diagnosis and treatment.

Indexed as

AlgorithmsAdolescentAdultAgedAged, 80 and overBayes TheoremFemaleHepatic EncephalopathyHepatorenal SyndromeHumansLiver CirrhosisLogistic ModelsMaleMiddle AgedMultivariate AnalysisRisk Factors

Identifiers

PMID31000773
PMCPMC6472503
OpenAlexW2939924008

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.