Evidence map›Paper›PMID 31001211›Full record

ArticleFrontiers in microbiology2019

Structural and Functional Characterization of the Type Three Secretion System (T3SS) Needle of

Charlotte Lombardi, James Tolchard, Stephanie Bouillot, Luca Signor, Caroline Gebus, David Liebl, Daphna Fenel, Jean-Marie Teulon, Juliane Brock, Birgit Habenstein and 6 more

Abstract read
In one paragraph

Article in Frontiers in microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Article
  2. Article
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  4. International journal of systematic and evolutionary microbiology · 2024
    Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Review
  13. Review
  14. Article
  15. Modulation of the immune response by theFrontiers in cellular and infection microbiology · 2022
    Review
  16. Review
  17. Article
  18. Review
  19. Article
  20. Relationship of biofilm-forming ability of with swimming motility, twitching motility and virulence gene distribution.Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Charlotte LombardiUniv. Grenoble Alpes, CEA, CNRS, Institut de Biologie Structurale (IBS), Grenoble, France.
James TolchardInstitute of Chemistry and Biology of Membranes and Nanoobjects, Institut Européen de Chimie et Biologie (CBMN), UMR5248 CNRS, University of Bordeaux, Pessac, France.
Stephanie BouillotUniv. Grenoble Alpes, Bacterial Pathogenesis and Cellular Responses Group, U1036 INSERM, ERL5261 CNRS, CEA, Grenoble, France.
Luca SignorUniv. Grenoble Alpes, CEA, CNRS, Institut de Biologie Structurale (IBS), Grenoble, France.
Caroline GebusUniv. Grenoble Alpes, Bacterial Pathogenesis and Cellular Responses Group, U1036 INSERM, ERL5261 CNRS, CEA, Grenoble, France.
David LieblUniv. Grenoble Alpes, Bacterial Pathogenesis and Cellular Responses Group, U1036 INSERM, ERL5261 CNRS, CEA, Grenoble, France.
Daphna FenelUniv. Grenoble Alpes, CEA, CNRS, Institut de Biologie Structurale (IBS), Grenoble, France.
Jean-Marie TeulonUniv. Grenoble Alpes, CEA, CNRS, Institut de Biologie Structurale (IBS), Grenoble, France.
Juliane BrockUniv. Grenoble Alpes, CEA, CNRS, Institut de Biologie Structurale (IBS), Grenoble, France.
Birgit HabensteinInstitute of Chemistry and Biology of Membranes and Nanoobjects, Institut Européen de Chimie et Biologie (CBMN), UMR5248 CNRS, University of Bordeaux, Pessac, France.
Jean-Luc PellequerUniv. Grenoble Alpes, CEA, CNRS, Institut de Biologie Structurale (IBS), Grenoble, France.
Eric FaudryUniv. Grenoble Alpes, Bacterial Pathogenesis and Cellular Responses Group, U1036 INSERM, ERL5261 CNRS, CEA, Grenoble, France.
Antoine LoquetInstitute of Chemistry and Biology of Membranes and Nanoobjects, Institut Européen de Chimie et Biologie (CBMN), UMR5248 CNRS, University of Bordeaux, Pessac, France.
Ina AttréeUniv. Grenoble Alpes, Bacterial Pathogenesis and Cellular Responses Group, U1036 INSERM, ERL5261 CNRS, CEA, Grenoble, France.
Andréa DessenUniv. Grenoble Alpes, CEA, CNRS, Institut de Biologie Structurale (IBS), Grenoble, France.
Viviana JobUniv. Grenoble Alpes, CEA, CNRS, Institut de Biologie Structurale (IBS), Grenoble, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The type three secretion system (T3SS) is a macromolecular protein nano-syringe used by different bacterial pathogens to inject effectors into host cells. The extracellular part of the syringe is a needle-like filament formed by the polymerization of a 9-kDa protein whose structure and proper localization on the bacterial surface are key determinants for efficient toxin injection. Here, we combined

Indexed as

immunofluorescence microscopymutagenesisPseudomonas aeruginosastructureT3SS needletype III secretion systemvirulence

Identifiers

PMID31001211
PMCPMC6455054

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.