ArticleDiabetes2019
Microbiota-Produced
Open access · bronzeAbstract read
In one paragraph
Article in Diabetes, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 33 citations in OpenAlex.
- The Role of Kupffer Cells and Liver Macrophages in the Pathogenesis of Metabolic Dysfunction-Associated Steatotic Liver Disease.Biomedicines · 2026Review
- N-formyl methionine peptide-driven neutrophil activation in idiopathic inflammatory myopathies.Rheumatology (Oxford, England) · 2026Article
- NMR based human gut metabolomic profiling reveals altered metabolites associated with pulmonary and extra-pulmonary tuberculosis.Metabolomics : Official journal of the Metabolomic Society · 2025Article
- Monoclonal Antibody 5F1 Modulates Formyl Peptide Receptor 1 Conformation for Transmembrane Signaling.FASEB bioAdvances · 2025Article
- Bioactive Compounds as Modulators of N-Formyl Peptide Signaling in Chronic Diseases.Molecules (Basel, Switzerland) · 2025Review
- The role of exosomes for sustained specific cardiorespiratory and metabolic improvements in males with type 2 diabetes after detraining.EBioMedicine · 2024Article
- Formylated Peptide Receptor-1-Mediated Gut Inflammation as a Therapeutic Target in Inflammatory Bowel Disease.Crohn's & colitis 360 · 2024Article
- FPR1, as a Potential Biomarker of Diagnosis and Infliximab Therapy Responses for Crohn's Disease, is Related to Disease Activity, Inflammation and Macrophage Polarization.Journal of inflammation research · 2024Article
- WKYMVm ameliorates obesity by improving lipid metabolism and leptin signalling.Journal of cellular and molecular medicine · 2023Article
- Modified Signaling of Membrane Formyl Peptide Receptors in NADPH-Oxidase Regulation in Obesity-Resistant Mice.Membranes · 2023Article
- Rs867228 in FPR1 accelerates the manifestation of luminal B breast cancer.Oncoimmunology · 2023Article
- Formyl peptide receptor-1 (FPR1) represses intestinal oncogenesis.Oncoimmunology · 2023Article
- Gut lumen-leaked microbial DNA causes myocardial inflammation and impairs cardiac contractility in ageing mouse heart.Frontiers in immunology · 2023Article
- Microbial DNA enrichment promotes liver steatosis and fibrosis in the course of non-alcoholic steatohepatitis.Acta physiologica (Oxford, England) · 2022Article
- Accumulation of microbial DNAs promotes to islet inflammation and β cell abnormalities in obesity in mice.Nature communications · 2022Article
- Genomic loci mispositioning in Tmem120a knockout mice yields latent lipodystrophy.Nature communications · 2022Article
- Gut Microbiota: An Important Player in Type 2 Diabetes Mellitus.Frontiers in cellular and infection microbiology · 2022Review
- Formyl peptide receptor 1 promotes podocyte injury through regulation of mitogen-activated protein kinase pathways.Experimental biology and medicine (Maywood, N.J.) · 2022Article
- Gut microbiota-derived metabolites as key mucosal barrier modulators in obesity.World journal of gastroenterology · 2021Review
- CRIgGastroenterology · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors at 3 institutions in 1 country.
Joshua WollamDivision of Endocrinology and Metabolism, Department of Medicine, University of California, San Diego, La Jolla, CA.
Matthew RiopelDivision of Endocrinology and Metabolism, Department of Medicine, University of California, San Diego, La Jolla, CA.
Yong-Jiang XuDivision of Endocrinology and Metabolism, Department of Medicine, University of California, San Diego, La Jolla, CA.
Andrew M F JohnsonDivision of Endocrinology and Metabolism, Department of Medicine, University of California, San Diego, La Jolla, CA.
Jachelle M OfrecioDivision of Endocrinology and Metabolism, Department of Medicine, University of California, San Diego, La Jolla, CA.
Wei YingDivision of Endocrinology and Metabolism, Department of Medicine, University of California, San Diego, La Jolla, CA.
Dalila El OuarratDivision of Endocrinology and Metabolism, Department of Medicine, University of California, San Diego, La Jolla, CA.
Luisa S ChanSecond Genome, Inc., South San Francisco, CA.
Andrew W HanSecond Genome, Inc., South San Francisco, CA.
Nadir A MahmoodSecond Genome, Inc., South San Francisco, CA.
Caitlin N RyanSecond Genome, Inc., South San Francisco, CA.
Yun Sok LeeDivision of Endocrinology and Metabolism, Department of Medicine, University of California, San Diego, La Jolla, CA.
Jeramie D WatrousDivision of Endocrinology and Metabolism, Department of Medicine, University of California, San Diego, La Jolla, CA.
Mahendra D ChordiaDepartment of Radiology and Medical Imaging, University of Virginia, Charlottesville, VA.
Dongfeng PanDepartment of Radiology and Medical Imaging, University of Virginia, Charlottesville, VA.
Mohit JainDivision of Endocrinology and Metabolism, Department of Medicine, University of California, San Diego, La Jolla, CA.
Jerrold M OlefskyDivision of Endocrinology and Metabolism, Department of Medicine, University of California, San Diego, La Jolla, CA jolefsky@ucsd.edu.ORCID 0000-0003-0392-1705
University of California San Diego · USSecond Genome (United States) · USUniversity of Virginia · US
Funding
Transgenic & Knock-out MouseP30DK063491 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MILES Frome WILKINSON · 2003 to 2026
$40.4MTranscriptional Genomics CoreP01DK074868 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ROSENFELD, M · 2007 to 2016
$16.6MU of Calif, San Diego Neuroscience Microscopy ImagingP30NS047101 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GLEESON, JOSEPH G, ZHENG, BINHAI · 2003 to 2022
$9.0MINSULIN RECEPTORS AND THE GLUCOSE TRANSPORT SYSTEMR37DK033651 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI OLEFSKY, JERROLD MICHAEL · 2000 to 2010
$6.1MTRAINING PROGRAM IN DIABETES RESEARCHT32DK007494 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SALTIEL, ALAN R. · 1986 to 2021
$4.7MMapping the Plasma Exposome and its Association with Human Cardiovascular DiseaseR01ES027595 · NIEHS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JAIN, MOHIT · 2017 to 2021
$3.3MINSULIN RECEPTORS AND THE GLUCOSE TRANSPORT SYSTEMR01DK033651 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI OLEFSKY, JERROLD MICHAEL · 1986 to 2013
$2.2MEffects of Fractalkine on Beta Cell FunctionR01DK101395 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI OLEFSKY, JERROLD MICHAEL · 2014 to 2017
$1.6MRapidFire mass spectrometry systemS10OD020025 · OD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JAIN, MOHIT · 2015 to 2015
$600kA Gut Microbiome Metabolite Axis in Obesity-Associated Inflammation and Insulin ResistanceF32DK105686 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI WOLLAM, JOSHUA PAUL · 2015 to 2016
$116kNIDDK NIH HHS F32 DK105686NIDDK NIH HHS P01 DK074868NIDDK NIH HHS P30 DK063491NIDDK NIH HHS R01 DK033651NIDDK NIH HHS R01 DK101395NIDDK NIH HHS R37 DK033651NIDDK NIH HHS T32 DK007494NIEHS NIH HHS R01 ES027595NIH HHS S10 OD020025NINDS NIH HHS P30 NS047101
Abstract
The composition of the gastrointestinal microbiota and associated metabolites changes dramatically with diet and the development of obesity. Although many correlations have been described, specific mechanistic links between these changes and glucose homeostasis remain to be defined. Here we show that blood and intestinal levels of the microbiota-produced
Indexed as
AnimalsCells, CulturedChemotaxisChromatography, LiquidDiet, High-FatEnzyme-Linked Immunosorbent AssayFlow CytometryGlucagon-Like Peptide 1GlucoseGlucose IntoleranceIn Situ Hybridization, FluorescenceInsulinMaleMass SpectrometryMiceMice, KnockoutGlucagon-Like Peptide 1GlucoseInsulinOligopeptides
Identifiers
What Socratic holds
Textmetadata
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.