ReviewPflugers Archiv : European journal of physiology2020
Cardiac adaptation to exercise training in health and disease.
Review in Pflugers Archiv : European journal of physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed.
- Orthostatic-dependent cardiopulmonary responses among trained females during intensity matched resistance exercises in a pilot randomized crossover study.Scientific reports · 2025Trial
- Sprint Interval Running and Continuous Running Produce Training Specific Adaptations, Despite a Similar Improvement of Aerobic Endurance Capacity-A Randomized Trial of Healthy Adults.International journal of environmental research and public health · 2020Trial
- Exploring the role of CaMKII in exercise-induced cardioprotection.Human cell · 2026Review
- Mechanoreceptor-mediated adaptations to physical exercise: from acute responses to long-term training effects.Cellular and molecular life sciences : CMLS · 2026Review
- Physical Activity and Its Impact on Cardiometabolic Disorders.Handbook of experimental pharmacology · 2026Review
- Effect of contralateral limb exercise on peripheral perfusion index in a resting limb.The Indian journal of medical research · 2025Article
- Longer Health Resort Therapy Improves Outcomes in Long COVID: A Retrospective Study.Medicina (Kaunas, Lithuania) · 2025Article
- Adaptive Changes in Endurance Athletes: A Review of Molecular, Echocardiographic and Electrocardiographic Findings.International journal of molecular sciences · 2025Review
- Effects of squat training on energy expenditure, oxygen consumption, and heart rate in young healthy adults.Scientific reports · 2025Article
- Regulatory mechanisms of exercise-induced physiological cardiac hypertrophy: progress and prospects.Frontiers in cardiovascular medicine · 2025Review
- Treating Cardiovascular Disorders with Personalized Medicine.Cardiovascular & hematological disorders drug targets · 2025Review
- Concurrent training and intermittent fasting reduce transverse cross-sectional area of cardiomyocytes and body mass in Wistar rats.Frontiers in physiology · 2025Article
- Revisiting the concept of bout: associations of moderate-to-vigorous physical activity sessions and non-sessions with mortality.The international journal of behavioral nutrition and physical activity · 2024Article
- Investigation of left atrial mechanical function and left ventricular systolic and diastolic parameters in athletes performing resistance exercise and combined exercise.BMC cardiovascular disorders · 2024Article
- Intrinsic and Extrinsic Contributors to the Cardiac Benefits of Exercise.JACC. Basic to translational science · 2024Review
- Assessment of descending aortic blood flow velocities with continuous wave Doppler echocardiography among healthy Children in South East Nigeria.Malawi medical journal : the journal of Medical Association of Malawi · 2024Article
- Different exercise training intensities prevent type 2 diabetes mellitus-induced myocardial injury in male mice.iScience · 2023Article
- Telocytes response to cardiac growth induced by resistance exercise training and endurance exercise training in adult male rats.The journal of physiological sciences : JPS · 2023Article
- Myokine Musclin Is Critical for Exercise-Induced Cardiac Conditioning.International journal of molecular sciences · 2023Article
- Can the WHO 's recommendations of physical activity volume decrease the risk of heart disease in middle and older aged Chinese People: the evidence from a seven year longitudinal survey.BMC geriatrics · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The heart is the primary pump that circulates blood through the entire cardiovascular system, serving many important functions in the body. Exercise training provides favorable anatomical and physiological changes that reduce the risk of heart disease and failure. Compared with pathological cardiac hypertrophy, exercise-induced physiological cardiac hypertrophy leads to an improvement in heart function. Exercise-induced cardiac remodeling is associated with gene regulatory mechanisms and cellular signaling pathways underlying cellular, molecular, and metabolic adaptations. Exercise training also promotes mitochondrial biogenesis and oxidative capacity leading to a decrease in cardiovascular disease. In this review, we summarized the exercise-induced adaptation in cardiac structure and function to understand cellular and molecular signaling pathways and mechanisms in preclinical and clinical trials.
Indexed as
Identifiers
31016384What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.