Evidence mapPaperPMID 31025085Full record

ReviewSeminars in immunopathology2019

Impact of bariatric surgery on type 2 diabetes: contribution of inflammation and gut microbiome?

Jean Debédat, Chloé Amouyal, Judith Aron-Wisnewsky, Karine Clément

Abstract readReview
PubMed Publisher
In one paragraph

Review in Seminars in immunopathology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. THE INTESTINAL MICROBIOME IN PATIENTS UNDERGOING BARIATRIC SURGERY: A SYSTEMATIC REVIEW.Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2022 · on this map
    Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. The human microbiome in disease and pathology.APMIS : acta pathologica, microbiologica, et immunologica Scandinavica · 2022
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Gut microbiota differs a decade after bariatric surgery relative to a nonsurgical comparison group.Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery · 2020
    Observational
  15. Review
  16. Review
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jean DebédatSorbonne Université, INSERM UMRS, Nutrition and Obesities; Systemic Approaches (NutriOmics), 47-83 Bd de l'hôpital, 75013, Paris, France.
Chloé AmouyalSorbonne Université, INSERM UMRS, Nutrition and Obesities; Systemic Approaches (NutriOmics), 47-83 Bd de l'hôpital, 75013, Paris, France.
Judith Aron-WisnewskySorbonne Université, INSERM UMRS, Nutrition and Obesities; Systemic Approaches (NutriOmics), 47-83 Bd de l'hôpital, 75013, Paris, France. judith.aron-wisnewsky@psl.aphp.fr.
Karine ClémentSorbonne Université, INSERM UMRS, Nutrition and Obesities; Systemic Approaches (NutriOmics), 47-83 Bd de l'hôpital, 75013, Paris, France. karine.clement@inserm.fr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Obesity is a chronic low-grade inflammatory disease (both at the systemic and adipose tissue level) that continues to rise worldwide. It is associated with an abundance of comorbidities, including type 2 diabetes (T2D). Bariatric surgery, which induces modifications of the intestinal tract, is to date the most successful treatment for obesity. Its use has dramatically increased in number as it enables both weight reduction and metabolic improvements, with 60% of patients even achieving diabetes remission. Several mechanisms are actually demonstrated to be involved in those clinical improvements. Importantly, both obesity and T2D share many phenotypic characteristics, including increased systemic and adipose tissue inflammation, as well as gut microbiota dysbiosis. These characteristics are deeply modulated after bariatric surgery. This review will address the host metabolic changes observed after bariatric surgery, focusing on the induced gut architectural changes, as well as on the modifications of the inflammatory tone and the gut microbiota.

Indexed as

Diabetes Mellitus, Type 2DysbiosisGastrointestinal MicrobiomePostoperative ComplicationsAdipose TissueBariatric SurgeryHumansInflammationObesityBariatric surgeryGut microbiotaInflammationMicrobiomeObesityType 2 diabetes

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.