Evidence map›Paper›PMID 31027159›Full record

ArticleMetabolites2019

Surfactant Lipidomics of Alveolar Lavage Fluid in Mice Based on Ultra-High-Performance Liquid Chromatography Coupled to Hybrid Quadrupole-Exactive Orbitrap Mass Spectrometry.

Rui Yang, Ying Zhang, Wenjuan Qian, Linxiu Peng, Lili Lin, Jia Xu, Tong Xie, Jianjian Ji, Xiuqin Zhan, Jinjun Shan

Open access · goldAbstract read
In one paragraph

Article in Metabolites, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
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  5. Review
  6. Therapeutic mechanism ofFrontiers in pharmacology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Rui YangJiangsu Key Laboratory of Pediatric Respiratory Disease, School of Medicine and Life Sciences, Nanjing University of Chinese Medicine, Nanjing 210023, China. 20171349@njucm.edu.cn.
Ying ZhangGenome Center of UC Davis, NIH West Coast Metabolomics Center, Davis, CA 95616, USA. yzhang1088@gmail.com.
Wenjuan QianJiangsu Key Laboratory of Pediatric Respiratory Disease, School of Medicine and Life Sciences, Nanjing University of Chinese Medicine, Nanjing 210023, China. 20161325@njucm.edu.cn.
Linxiu PengMedical Metabolomics Center, Nanjing University of Chinese Medicine, Nanjing 210023, China. penglx01@163.com.
Lili LinMedical Metabolomics Center, Nanjing University of Chinese Medicine, Nanjing 210023, China. linnj@njucm.edu.cn.
Jia XuMedical Metabolomics Center, Nanjing University of Chinese Medicine, Nanjing 210023, China. njxj0106@126.com.
Tong XieMedical Metabolomics Center, Nanjing University of Chinese Medicine, Nanjing 210023, China. sunnyxyl1021@163.com.
Jianjian JiInstitute of Pediatrics, Nanjing University of Chinese Medicine, Nanjing 210023, China. Jijj@njucm.edu.cn.
Xiuqin ZhanJiangsu Key Laboratory of Pediatric Respiratory Disease, School of Medicine and Life Sciences, Nanjing University of Chinese Medicine, Nanjing 210023, China. xqzhan14@sina.com.
Jinjun ShanJiangsu Key Laboratory of Pediatric Respiratory Disease, School of Medicine and Life Sciences, Nanjing University of Chinese Medicine, Nanjing 210023, China. jshan@njucm.edu.cn.ORCID 0000-0001-8079-7950
Nanjing University of Chinese Medicine · CNJoint Center for Structural Genomics · US

Funding

Jiangsu Provincial 333 High Levels Talents Cultivation Project BRA2016427Jiangsu Provincial Six Talent Peaks Project YY-022Major Research Plan of Natural Science Foundation of the Higher Education Institutions of Jiangsu Province 16KJA360002, 17KJB360007National Natural Science Foundation of China No.81774156Natural Science Foundation of Jiangsu Province BK20161573the Project of the Priority Academic Program Development of Jiangsu Higher Education Institutions PAPD
6 · The paper itself

Abstract

Surfactant lipid metabolism is closely related to pulmonary diseases. Lipid metabolism disorder can cause lung diseases, vice versa. With this rationale, a useful method was established in this study to determine the lipidome in bronchoalveolar lavage fluid (BALF) of mice. The lipid components in BALF were extracted by liquid-liquid extraction (methanol and methyl tert-butyl ether, and water). Ultra-high-performance liquid chromatography coupled to hybrid Quadrupole-Exactive Orbitrap mass spectrometry was used to analyze the extracted samples, which showed a broad scanning range of 215-1800

Indexed as

acute lung injurybronchoalveolar lavage fluidhigh-resolution mass spectrometrylipopolysaccharidesurfactant lipidomics

Identifiers

PMID31027159
PMCPMC6523637
OpenAlexW2940847401

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.