Evidence map›Paper›PMID 31027191›Full record

Trial reportNutrients2019

Local In Vivo Measures of Muscle Lipid and Oxygen Consumption Change in Response to Combined Vitamin D Repletion and Aerobic Training in Older Adults.

D Travis Thomas, David M Schnell, Maja Redzic, Mingjun Zhao, Hideat Abraha, Danielle Jones, Howard Brim, Guoqiang Yu

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

D Travis ThomasCollege of Health Sciences, University of Kentucky, Lexington, KY 40536, USA. dth225@uky.edu.ORCID 0000-0002-3593-5151
David M SchnellDepartment of Pharmacology & Nutritional Sciences, University of Kentucky, Lexington, KY 40536, USA. dave.schnell@uky.edu.
Maja RedzicDepartment of Pharmacology & Nutritional Sciences, University of Kentucky, Lexington, KY 40536, USA. mre226@g.uky.edu.
Mingjun ZhaoDepartment of Biomedical Engineering, University of Kentucky, Lexington, KY 40536, USA. mingjun.zhao@uky.edu.
Hideat AbrahaDepartment of Pharmacology & Nutritional Sciences, University of Kentucky, Lexington, KY 40536, USA. hideat.abraha@gmail.com.
Danielle JonesDepartment of Pharmacology & Nutritional Sciences, University of Kentucky, Lexington, KY 40536, USA. Danielle.Jones@uky.edu.
Howard BrimDepartment of Biomedical Engineering, University of Kentucky, Lexington, KY 40536, USA. howard.brim@uky.edu.
Guoqiang YuDepartment of Biomedical Engineering, University of Kentucky, Lexington, KY 40536, USA. gyu2@uky.edu.
University of Kentucky · US

Funding

University of Kentucky Markey Cancer Center Support Grant ECIA SupplementP30CA177558 · NCI · UNIVERSITY OF KENTUCKY · PI Bernard Mark Evers · 2013 to 2026
$38.3M
Kentucky Center for Clinical and Translational ScienceUL1TR001998 · NCATS · UNIVERSITY OF KENTUCKY · PI HARTMANN, KATHERINE E, KERN, PHILIP A · 2016 to 2025
$34.2M
University of Kentucky Center for Cancer MetabolismP20GM121327 · NIGMS · UNIVERSITY OF KENTUCKY · PI Binhua P Zhou · 2017 to 2026
$25.0M
TRAINING PROGRAM IN OXIDATIVE STRESS AND NUTRITIONT32DK007778 · NIDDK · UNIVERSITY OF KENTUCKY · PI WEBB, NANCY R · 2000 to 2019
$2.5M
Essential Siemens Prisma Fit Upgrade for the University of Kentucky 3T Research ScannerS10OD023573 · OD · UNIVERSITY OF KENTUCKY · PI SMITH, CHARLES DENNIS · 2017 to 2017
$813k
Vitamin D Contribution to Muscle Metabolic Function in the ElderlyR21AG046762 · NIA · UNIVERSITY OF KENTUCKY · PI THOMAS, DAVID TRAVIS · 2014 to 2015
$396k
NCI NIH HHS P30 CA177558NIDDK NIH HHS T32 DK007778NIGMS NIH HHS P20 GM121327NIH HHS 1P20GM121327-01NIH HHS R21AG046762NIH HHS S10 OD023573NIH HHS T32DK007778-16NIH HHS UL1TR001998
6 · The paper itself

Abstract

Intramyocellular (IMCL), extramyocellular lipid (EMCL), and vitamin D deficiency are associated with muscle metabolic dysfunction. This study compared the change in [IMCL]:[EMCL] following the combined treatment of vitamin D and aerobic training (DAT) compared with vitamin D (D), aerobic training (AT), and control (CTL). Male and female subjects aged 60-80 years with a BMI ranging from 18.5-34.9 and vitamin D status of ≤32 ng/mL (25(OH)D) were recruited to randomized, prospective clinical trial double-blinded for supplement with a 2 × 2 factorial design. Cholecalciferol (Vitamin D

Indexed as

ExerciseAgedDietary SupplementsFemaleHumansLipid MetabolismMaleMiddle AgedMuscle, SkeletalOxygen ConsumptionVitamin DVitamin DIMCLmetabolic functionsarcopeniaskeletal musclevitamin D

Identifiers

PMID31027191
PMCPMC6521174
OpenAlexW2941969707

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.