Evidence map›Paper›PMID 31035479›Full record

ArticleNutrients2019

The Association of Life's Simple 7 with Aldosterone among African Americans in the Jackson Heart Study.

Veena Kesireddy, Yubo Tan, David Kline, Guy Brock, James B Odei, Bjorn Kluwe, Valery S Effoe, Justin B Echouffo Tcheugui, Rita R Kalyani, Mario Sims and 4 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 1 country.

Veena KesireddyDepartment of Medicine, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA. veena.kesireddy@osumc.edu.
Yubo TanDepartment of Biomedical Informatics and Center for Biostatistics, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA. yubo.tan@osumc.edu.
David KlineDepartment of Biomedical Informatics and Center for Biostatistics, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA. david.kline@osumc.edu.ORCID 0000-0001-6183-3303
Guy BrockDepartment of Biomedical Informatics and Center for Biostatistics, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA. guy.brock@osumc.edu.ORCID 0000-0001-5317-079X
James B OdeiDivision of Biostatistics, College of Public Health, The Ohio State University, Columbus, OH 43210, USA. odei@stat.osu.edu.
Bjorn KluweDepartment of Medicine, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA. kluwe.3@buckeyemail.osu.edu.
Valery S EffoeDepartment of Medicine, Morehouse School of Medicine, Atlanta, GA 30310, USA. VEffoe@msm.edu.
Justin B Echouffo TcheuguiDivision of Endocrinology, Diabetes, and Metabolism, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA. jechouf1@jhmi.edu.
Rita R KalyaniDivision of Endocrinology, Diabetes, and Metabolism, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA. rita.kalyani@gmail.com.
Mario SimsDepartment of Medicine, University of Mississippi Medical Center, Jackson, MS 39216, USA. msims2@umc.edu.
Herman A TaylorDepartment of Medicine, Morehouse School of Medicine, Atlanta, GA 30310, USA. htaylor@msm.edu.
Morgana Mongraw-ChaffinDepartment of Epidemiology & Prevention, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA. mmongraw@wakehealth.edu.
Ehimare AkhabueDivision of Cardiovascular Diseases and Hypertension, Rutgers University Robert Wood Johnson Medical School, New Brunswick, NJ 08901, USA. ehimare.akhabue@rutgers.edu.
Joshua J JosephDepartment of Medicine, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA. joseph.117@osu.edu.ORCID 0000-0001-9169-8261
The Ohio State University Wexner Medical Center · USJohns Hopkins University · USMorehouse School of Medicine · USRutgers, The State University of New Jersey · USThe Ohio State University · USUniversity of Mississippi Medical Center · USWake Forest University · US

Funding

NHLBI NIH HHS 1 R01 HL117285-01NHLBI NIH HHS HHSN268201300046C, HHSN268201300047C, HHSN268201300048C, HHSN268201300049C, and HHSN268201300050CNIDDK NIH HHS K23DK117041NIMHD NIH HHS HHSN268201300046C, HHSN268201300047C, HHSN268201300048C, HHSN268201300049C, and HHSN268201300050C
6 · The paper itself

Abstract

backgroundAmong African Americans (AAs), attaining higher levels of American Heart Association (AHA) ideal cardiovascular health (Life's Simple 7 [LS7]) is associated with lower risk of diabetes and cardiovascular disease (CVD). We previously showed that aldosterone is associated with higher risk of diabetes and CVD in AAs. Thus, we investigated the association of LS7 metrics with aldosterone in the Jackson Heart Study (JHS).

methodsIdeal metrics were defined by AHA 2020 goals for health behaviors (smoking, dietary intake, physical activity, and body mass index) and health factors (total cholesterol, blood pressure, and fasting glucose). The number of ideal LS7 metrics attained at baseline were summed into a continuous score (0-7) and categorical groups (Poor: 0-1, Intermediate: 2-3, and Ideal: ≥4 ideal LS7 metrics). Multivariable linear regression was used.

resultsAmong 4,095 JHS participants (mean age 55 ± 13 years, 65% female), median serum aldosterone was 4.90, 4.30, and 3.70 ng/dL in the poor (

conclusionsHigher attainment of ideal LS7 metrics was associated with lower serum aldosterone among AAs with a greater magnitude of association among women compared to men.

Indexed as

Black or African AmericanAdultAgedAged, 80 and overAldosteroneBlood GlucoseFemaleHeart DiseasesHumansMaleMiddle AgedMississippiProspective StudiesYoung AdultAldosteroneBlood GlucoseAfrican Americansaldosteroneblood pressurebody mass indexcholesterol.glucoseideal cardiovascular healthLife’s Simple 7physical activitysmoking

Identifiers

PMID31035479
PMCPMC6566676
OpenAlexW2940704136

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.