Evidence map›Paper›PMID 31036044›Full record

ArticleParasites & vectors2019

African trypanosomes.

Mathieu Cayla, Federico Rojas, Eleanor Silvester, Frank Venter, Keith R Matthews

Open access · goldAbstract read
In one paragraph

Article in Parasites & vectors, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 48 citations in OpenAlex.

  1. International journal for parasitology. Parasites and wildlife · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Trypanosomiasis: An emerging disease in Alpine swift (International journal for parasitology. Parasites and wildlife · 2024
    Article
  8. ACS omega · 2023
    Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Phloroglucinol as a Potential Candidate againstMolecules (Basel, Switzerland) · 2022
    Article
  16. Article
  17. Article
  18. Article
  19. The Occurrence of Malignancy inFrontiers in microbiology · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Mathieu CaylaInstitute for Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, Edinburgh, UK.
Federico RojasInstitute for Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, Edinburgh, UK.
Eleanor SilvesterInstitute for Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, Edinburgh, UK.
Frank VenterInstitute for Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, Edinburgh, UK.
Keith R MatthewsInstitute for Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, Edinburgh, UK. keith.matthews@ed.ac.uk.
University of Edinburgh · GB

Funding

Wellcome Trust 103740/Z/14/ZWellcome Trust 103740/Z14/ZWolfson Foundation WM140045
6 · The paper itself

Abstract

African trypanosomes cause human African trypanosomiasis and animal African trypanosomiasis. They are transmitted by tsetse flies in sub-Saharan Africa. Although most famous for their mechanisms of immune evasion by antigenic variation, there have been recent important studies that illuminate important aspects of the biology of these parasites both in their mammalian host and during passage through their tsetse fly vector. This Primer overviews current research themes focused on these parasites and discusses how these biological insights and the development of new technologies to interrogate gene function are being used in the search for new approaches to control the parasite. The new insights into the biology of trypanosomes in their host and vector highlight that we are in a 'golden age' of discovery for these fascinating parasites.

Indexed as

Host-Parasite InteractionsAfrica South of the SaharaAnimalsHumansInsect VectorsTrypanosomaTrypanosoma brucei bruceiTrypanosomiasis, AfricanTsetse FliesSleeping sicknessTrypanosoma bruceiTrypanosome

Identifiers

PMID31036044
PMCPMC6489224
OpenAlexW4211099798

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.