Evidence map›Paper›PMID 31049873›Full record

Trial reportAdvances in therapy2019

Impact of a Community Pharmacist-Delivered Information Program on the Follow-up of Type-2 Diabetic Patients: A Cluster Randomized Controlled Study.

Yves Michiels, Olivier Bugnon, Annie Chicoye, Sylvie Dejager, Christine Moisan, François-André Allaert, Catherine Hunault, Laura Romengas, Hubert Méchin, Bruno Vergès

Open access · hybridAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Advances in therapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 7 pooled it
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 7 syntheses or guidelines pooled it, 34 citations in OpenAlex.

  1. Pooled it
  2. Effective Education Methods to Improve Glycemic Control in Type 2 Diabetes Mellitus Patients: A Systematic Review.Journal of preventive medicine and public health = Yebang Uihakhoe chi · 2025
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  18. Pilot of interactive texting for diabetes self-management education and support.Journal of the American Pharmacists Association : JAPhA
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Yves MichielsCommunity Pharmacy, School of Pharmaceutical Sciences, University of Geneva, University of Lausanne, Lausanne, Switzerland.
Olivier BugnonCommunity Pharmacy, School of Pharmaceutical Sciences, University of Geneva, University of Lausanne, Lausanne, Switzerland.
Annie ChicoyeInstitut d'Études Politiques de Paris, Paris, France.
Sylvie DejagerMSD France, Courbevoie, France.
Christine MoisanDepartment of Diabetology, Pitie Salpetrière, Paris, France.
François-André AllaertEvaluation Chair BSB-Cenbiotech, Dijon, France.
Catherine HunaultMSD France, Courbevoie, France.
Laura RomengasObservia Group, Paris, France.
Hubert MéchinObservia Group, Paris, France.
Bruno VergèsDepartment of Endocrinology, Diabetology and Metabolic Diseases, CHU Dijon, Dijon, France. bruno.verges@chu-dijon.fr.ORCID 0000-0001-8957-629X
MSD (France) · FRUniversity of Geneva · CHCHU Dijon Bourgogne · FRInstitut d'Etudes Politiques de Paris · FRSorbonne Université · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionLow-quality communication between patients and care providers and limited patient knowledge of the disease and the therapy are important factors associated with poor glycemic control in patients with type 2 diabetes. We conducted a multicenter study to determine whether structured and tailored information delivered by pharmacists to type 2 diabetic patients could improve patient treatment adherence, hemoglobin A1c (HbA1c) levels and knowledge about diabetes.

methodsOne hundred seventy-four pharmacies were randomized to deliver an educational program on diet, drug treatment, disease and complications during three 30-min interviews over a 6-month period, or to provide no intervention, to type 2 diabetic patients treated with oral antidiabetic agents. Medication adherence was assessed by measuring the medication possession ratio and diabetes control by collecting HbA1c values. Levels of patient treatment self-management and disease knowledge were assessed using self-questionnaires.

resultsThree hundred seventy-seven patients were analyzed. The medication possession ratio, already very high at baseline in the intervention (94.8%) and control (92.3%) groups, did not vary significantly after 6 months with no difference between the two groups. Significant decreases in HbA1c were observed in both groups at 6 months (p < 0.001) and 12 months (p < 0.01), with significantly greater changes from baseline in the intervention group than in the control group at 6 months (- 0.5% vs. - 0.2%, p = 0.0047) and 12 months (- 0.6% vs. - 0.2%, p = 0.0057). Patients in the intervention group showed greater improvement in their ability to self-manage treatment (+ 4.86 vs. + 1.58, p = 0.0014) and in the extent of their knowledge about diabetes (+ 0.6 vs. + 0.2, p < 0.01) at 6 months versus baseline compared with the control group.

conclusionTailored information provided by the pharmacist to patients with type 2 diabetes did not significantly improve the already high adherence rates, but was associated with a significant decrease in HbA1c and an improvement of patient knowledge about diabetes.

trial registrationISRCTN33776525.

fundingMSD France.

Indexed as

Drug MonitoringPhysician-Patient RelationsAdultAgedAged, 80 and overCluster AnalysisDiabetes Mellitus, Type 2FemaleFollow-Up StudiesFranceHumansHyperglycemiaHypoglycemic AgentsMaleMiddle AgedPatient Education as TopicHypoglycemic AgentsDisease knowledgeGlucose controlPatient informationPharmacistType 2 diabetes

Identifiers

PMID31049873
PMCPMC6824455
OpenAlexW2943106583

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.