ArticleEuropean heart journal2020
Long-term blood pressure trajectories and incident atrial fibrillation in women and men: the Tromsø Study.
Article in European heart journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
38 citing papers in PubMed, 1 synthesis or guideline pooled it, 85 citations in OpenAlex.
- Pooled it
- Systolic Blood Pressure and Effects of Screening for Atrial Fibrillation With Long-Term Continuous Monitoring (a LOOP Substudy).Hypertension (Dallas, Tex. : 1979) · 2022Trial
- Incidence and Implications of Atrial Fibrillation/Flutter in Hypertension: Insights From the SPRINT Trial.Hypertension (Dallas, Tex. : 1979) · 2020Trial
- Prevalence and factors associated with atrial fibrillation among adults with type 2 diabetes mellitus at Hoima Regional Referral Hospital, Western Uganda: a cross-sectional study.Cardiovascular diabetology. Endocrinology reports · 2026Article
- Sex Differences in the Effect of Long-Term Blood Pressure Trajectories and Variability on the Atrial Fibrillation Risk in a Korean Cohort.Journal of Korean medical science · 2026Article
- Sex-Specific Blood Pressure Thresholds in Middle-Aged Adults.Hypertension (Dallas, Tex. : 1979) · 2026Article
- Trajectories of blood pressure measures and the incidence of electrocardiographic abnormalities: a worker-based cohort study.Frontiers in public health · 2026Article
- Association of resting heart rate trajectories with incident chronic kidney disease in patients with hypertension.Clinical hypertension · 2026Article
- Prospective associations between the trajectory of the Chinese visceral adiposity index and risk of new-onset heart failure.BMC public health · 2025Article
- Age-Specific Association Between Cumulative Blood Pressure Exposure and Atrial Fibrillation Risk in Adults.Journal of the American Heart Association · 2025Article
- Long-term pulse pressure trajectories and risk of incident atrial fibrillation: the Tromsø Study.European heart journal · 2025Article
- Spousal bereavement and its effects on later life physical and cognitive capability: the Tromsø study.GeroScience · 2024Article
- Blood Pressure Levels Within Target: Not Just Good Control But Excellent Control Over Time.JACC. Asia · 2024Article
- Relationship of the trajectory of the triglyceride-glucose index with heart failure: the Kailuan study.Lipids in health and disease · 2024Article
- Association of Estimated Glomerular Filtration Rate Trajectories with Atrial Fibrillation Risk in Populations with Normal or Mildly Impaired Renal Function.Kidney diseases (Basel, Switzerland) · 2024Article
- Causal effect of atrial fibrillation on pulmonary embolism: a mendelian randomization study.Journal of thrombosis and thrombolysis · 2024Article
- Trends in prevalence, treatment and control of hypertension in 38,825 adults over 36 years in Tromsø prospective study.Scandinavian journal of public health · 2023Article
- Association of hypertension severity and control with risk of incident atrial fibrillation: The REasons for Geographic And Racial Differences in Stroke (REGARDS) study.Clinical cardiology · 2023Article
- Association of blood pressure trajectories with coronary heart disease among the disabled population in Shanghai, China: a cohort study of 7 years following up.European journal of medical research · 2023Article
- Cardiovascular and renal multimorbidity increase risk of atrial fibrillation in the PREVEND cohort.Open heart · 2023Article
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsTo explore sex-specific associations between long-term individual blood pressure (BP) patterns and risk of incident atrial fibrillation (AF) in the general population. METHODS AND
resultsBlood pressure was measured in 8376 women and 7670 men who attended at least two of the three population-based Tromsø Study surveys conducted in 1986-87, 1994-95, and 2001. Participants were followed for incident AF throughout 2013. Latent mixed modelling was used to identify long-term trajectories of systolic BP and hypertension. Cox regression was used to estimate associations between the identified trajectories and incident AF. Elevated systolic BP throughout the exposure period (1986-2001) independently and differentially increased risk of AF in women and men. In women, having elevated systolic BP trajectories doubled AF risk compared to having persistently low levels, irrespective of whether systolic BP increased, decreased, or was persistently high over time, with hazard ratios of 1.88 (95% confidence interval 1.37-2.58), 2.32 (1.61-3.35), and 1.94 (1.28-2.94), respectively. In men, those with elevated systolic BP that continued to increase over time had a 50% increased AF risk: 1.51 (1.09-2.10). When compared to those persistently normotensive, women developing hypertension during the exposure period, and women and men with hypertension throughout the exposure period had 1.40 (1.06-1.86), 2.75 (1.99-3.80), and 1.36 (1.10-1.68) times increased risk of AF, respectively.
conclusionLong-term BP and hypertension trajectories were associated with increased incidence of AF in both women and men, but the associations were stronger in women.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.