Evidence map›Paper›PMID 31052231›Full record

ArticleInternational journal of molecular sciences2019

Effect of Ischemic Preconditioning and Postconditioning on Exosome-Rich Fraction microRNA Levels, in Relation with Electrophysiological Parameters and Ventricular Arrhythmia in Experimental Closed-Chest Reperfused Myocardial Infarction.

Andreas Spannbauer, Denise Traxler, Dominika Lukovic, Katrin Zlabinger, Johannes Winkler, Alfred Gugerell, Péter Ferdinandy, Derek J Hausenloy, Noemi Pavo, Maximilian Y Emmert and 4 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 30 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Overview of Cardiac Arrhythmias and Treatment Strategies.Pharmaceuticals (Basel, Switzerland) · 2023
    Review
  5. Article
  6. Diagnosis of Extracellular Vesicles in Cardiovascular and Metabolic Diseases.Advances in experimental medicine and biology · 2023
    Article
  7. Review
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Review
  14. MicroRNA Mediated Cardioprotection - Is There a Path to Clinical Translation?Frontiers in bioengineering and biotechnology · 2020
    Review
  15. Article
  16. Article
  17. Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 6 countries.

Andreas SpannbauerDepartment of Internal Medicine II, Division of Cardiology, Medical University of Vienna, 1090 Vienna, Austria. andreas.spannbauer@meduniwien.ac.at.ORCID 0000-0002-9819-0361
Denise TraxlerDepartment of Internal Medicine II, Division of Cardiology, Medical University of Vienna, 1090 Vienna, Austria. denise.traxler-weidenauer@meduniwien.ac.at.
Dominika LukovicDepartment of Internal Medicine II, Division of Cardiology, Medical University of Vienna, 1090 Vienna, Austria. dominika.lukovic@meduniwien.ac.at.
Katrin ZlabingerDepartment of Internal Medicine II, Division of Cardiology, Medical University of Vienna, 1090 Vienna, Austria. Katrin.zlabinger@meduniwien.ac.at.
Johannes WinklerDepartment of Internal Medicine II, Division of Cardiology, Medical University of Vienna, 1090 Vienna, Austria. Johannes.winkler@meduniwien.ac.at.
Alfred GugerellDepartment of Internal Medicine II, Division of Cardiology, Medical University of Vienna, 1090 Vienna, Austria. alfred.gugerell@meduniwien.ac.at.ORCID 0000-0002-5178-9967
Péter FerdinandyDepartment of Pharmacology and Pharmacotherapy, Semmelweis University, 1089 Budapest, Hungary. peter.ferdinandy@pharmahungary.com.
Derek J HausenloyNational Heart Centre Singapore, Singapore 169609, Singapore. d.hausenloy@ucl.ac.uk.
Noemi PavoDepartment of Internal Medicine II, Division of Cardiology, Medical University of Vienna, 1090 Vienna, Austria. noemi.pavo@meduniwien.ac.at.
Maximilian Y EmmertInstitute for Regenerative Medicine (IREM), University of Zurich, 8952 Zurich, Switzerland. Maximilian.Emmert@usz.ch.
Simon P HoerstrupInstitute for Regenerative Medicine (IREM), University of Zurich, 8952 Zurich, Switzerland. simon_philipp.hoerstrup@usz.ch.
Andras JakabCenter for MR-Research, University Children's Hospital Zurich, 8032 Zürich, Switzerland. Andras.Jakab@kispi.uzh.ch.ORCID 0000-0001-6291-9889
Mariann GyöngyösiDepartment of Internal Medicine II, Division of Cardiology, Medical University of Vienna, 1090 Vienna, Austria. mariann.gyongyosi@meduniwien.ac.at.ORCID 0000-0002-7083-2107
Martin RiesenhuberDepartment of Internal Medicine II, Division of Cardiology, Medical University of Vienna, 1090 Vienna, Austria. martin.riesenhuber@meduniwien.ac.at.
Medical University of Vienna · ATUniversity of Zurich · CHSemmelweis University · HUSt Bartholomew's Hospital · GBUniversity Children's Hospital Zurich · CH

Funding

COST Action EU-CARDIOPROTECTION CA16225 supported by COST (European Cooperation in Science and Technology). CA16225
6 · The paper itself

Abstract

We investigated the antiarrhythmic effects of ischemic preconditioning (IPC) and postconditioning (PostC) by intracardiac electrocardiogram (ECG) and measured circulating microRNAs (miRs) that are related to cardiac conduction. Domestic pigs underwent 90-min. percutaneous occlusion of the mid left anterior coronary artery, followed by reperfusion. The animals were divided into three groups: acute myocardial infarction (AMI,

Indexed as

Ischemic PostconditioningIschemic Preconditioning, MyocardialAnimalsExosomesFemaleHeart VentriclesMicroRNAsMyocardial InfarctionSwineVentricular FibrillationVentricular FunctionMicroRNAsacute myocardial infarctioncardiac electrophysiologyelectrocardiographyexosome-rich fractionexosomesextracellular vesiclesischemia-reperfusion injuryischemic postconditioningischemic preconditioningmiRNAreperfusion arrhythmiaventricular arrhythmia

Identifiers

PMID31052231
PMCPMC6540096
OpenAlexW2943231454

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.